Can cannabis calm the brain? new study scans Veterans' brains for clues

NCT ID NCT07222306

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Wayne State University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study will use brain scans to see how cannabis affects inflammation and brain activity in up to 100 U.S. military veterans with PTSD and suicidal thoughts. Participants will take cannabis for 12 weeks and have PET and MRI scans before and after. The goal is to link brain changes to improvements in PTSD symptoms and quality of life, which could help personalize cannabis-based treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabis (THC and CBD combinations)
What this could lead to: If successful, this could help identify which veterans with PTSD benefit most from cannabis-based treatments, leading to more personalized care.
What could go wrong: This is an early-stage imaging study, not a treatment trial. It may not show clear links between brain changes and symptom improvement, and results may not apply to all veterans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Behavior cannabis dependence Depression post-traumatic stress disorder Suicidal Ideation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSIVE SYMPTOMS PTSD PTSD SYMPTOMS SUICIDAL THOUGHTS AND BEHAVIORS

Contacts and locations

Locations

Tolan Park Medical Building

Detroit, Michigan, 48201, United States

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