DEPRESSIVE SYMPTOMS

This study tested whether a physical activity program delivered by mail and phone could help nearly 50,000 older women prevent heart attacks, strokes, falls, and hip fractures. Participants received exercise guides and tips to increase their daily activity. The goal was to see if…

This study tested an online mentoring program for transgender and gender minority youth ages 14 to 18. The program paired each teen with an adult transgender mentor for seven 90-minute sessions focused on building social and emotional skills. The goal was to see if the program co…

This study looked at whether taking daily vitamin D or fish oil supplements could prevent depression in over 18,000 healthy adults. Participants had no major depression history and took supplements or placebos for about 5 years. The results showed that neither vitamin D nor fish …

This study tested an online program called PROCARE-I+ to prevent anxiety and depression in 30 teenagers who were at high risk for emotional problems. The program helped improve their mood, quality of life, and ability to handle emotions. The study also found that family issues we…

This study tested a 6-week program that combines cognitive behavioral therapy, lifestyle advice, and communication skills for people caring for older adults in Hong Kong. The goal was to see if it could reduce stress, depression, and anxiety in caregivers. 255 caregivers took par…

This study tested whether a faith and prayer mobile app called PRAY.COM could help university students feel better mentally and emotionally. About 450 students used the app for at least 10 minutes each day over 8 weeks. Researchers checked if students liked the app and if it help…

This study tested a program called COPE (Coping Options for Parent Empowerment) for parents of teenagers in Spain. The goal was to see if it could help parents feel less anxious, depressed, and stressed, and improve their parenting skills. Twenty-six parents attended group sessio…

This study tested a mobile phone program designed to help children with cancer and their families build psychological strength and well-being. Forty participants used the app, and researchers measured its feasibility and potential benefits for mental health. The goal was to see i…

This study tested two ways to help adults with mild anxiety and depression in Spanish primary care. One was a 10-week group program, the other a single one-on-one session. Researchers tracked symptoms and healthcare use for 12 months to see which approach worked better.

This study tested whether a cultural arts program could reduce depressive symptoms and age-related self-stigma in older adults. 63 participants aged 60+ who were at risk for depression took part. The program involved creative arts activities, and results were compared to usual se…

This study tested a culturally adapted online therapy (iCBT) for Arabic-speaking refugee and migrant youth aged 15-29 with common mental health problems like anxiety, depression, and insomnia. 125 participants received either the therapy or were placed in a control group. The goa…

This study tested a talking therapy called Cognitive Processing Therapy (CPT) to help adults in Turkey who were struggling with PTSD, anxiety, and depression after the February 2023 earthquakes. 36 survivors took part, and the therapy aimed to reduce their distress and improve we…

This study tested whether audio-based digital programs can help reduce symptoms of depression. 101 adults with at least moderate depression were randomly assigned to listen to either a behavioral activation program or a self-monitoring program. Depression symptoms were measured b…

This study tested an 8-week smartphone-based cognitive behavioral therapy (CBT) program for 30 adults with psoriasis and mild to moderate depression. Participants used a coach-guided app to learn skills to manage their mood and skin condition. The goal was to see if the program w…

This pilot study tested a program called DAPPER for African American women aged 50 and older who have pain, depressive symptoms, and trouble moving around. Participants received 8 nurse visits at home to help them manage their pain and mood. The study measured changes in pain int…

This study tested an electronic mental health program (e-MHP) to see if it helps reduce depressive symptoms in adults. 70 people took part, including those diagnosed with mood disorders and healthy volunteers. The program's effect on depression severity was measured using a stand…

This pilot study tested a 10-session behavioral activation program delivered via teletherapy to increase physical activity and reduce depressive symptoms in 65 adults aged 18-64 with moderate-to-severe depression. Participants used a smartphone and Fitbit to track activity. The s…

This study looked at whether walking in nature can help reduce depressive symptoms in college students more than walking in a city. 138 students with mild to moderate depression were randomly assigned to urban walks, nature walks, or nature walks with guided activities. They walk…

This study tested a stepped-care program delivered by phone to help cancer survivors living in rural areas manage emotional distress like anxiety and depression. 68 adults who had finished cancer treatment for breast, colorectal, prostate, gynecologic cancers, or non-Hodgkin's ly…

This study tested a 5-week group program called Rare Group Problem Management Plus (PM+) for parents or guardians of children with rare diseases. The program, delivered by video, teaches practical and emotional coping skills. Eight caregivers took part, and the study checked if t…

This study looked at whether taking aspirin and ketamine by mouth at the same time can help adults whose depression hasn't improved with standard antidepressants. Fifteen people with treatment-resistant depression took the combination and were monitored for changes in their sympt…

This study tested whether a special type of strength training (flywheel) is better than traditional strength training at reducing depressive symptoms and improving physical and thinking skills in older women who are sedentary. Sixty-four women aged 60 and older participated in a …

This study explored whether daily training with different odors can improve both smell function and emotional well-being in people with mild depressive symptoms or major depression. Researchers enrolled 150 participants, including healthy volunteers and depressed patients, who pr…

This study looked at whether smelling lavender essential oil for 20 minutes before orthopedic surgery could lower anxiety, stress, and depression. 128 adults in Jordan took part, with half inhaling lavender oil and the other half receiving usual care. Results showed that those wh…

This study tested whether taking a probiotic called Lactobacillus reuteri can lower stress, anxiety, and depression in adults aged 18-45 who feel stressed. 150 participants took either the probiotic or a placebo for a period, and researchers measured their stress levels using que…

This study tested a version of cognitive behavioral therapy adapted for Turkish culture to help people who survived the earthquakes. 60 adults with high distress took part. The goal was to see if this therapy could reduce their psychological distress and depression and improve th…

This study tested a mobile web-based program designed to reduce stress and depression in people caring for a loved one with Alzheimer's disease. 184 caregivers aged 40 or older who provided at least 20 hours of in-home care per week and had mild depressive symptoms took part. The…

This study looked at how college students develop and handle stress. 120 students with mild-to-moderate depressive symptoms who were not in therapy took part. Some received weekly surveys and personalized feedback via text message, while others only completed surveys. The goal wa…

This study tested a free online program designed to improve mental well-being in people with myasthenia gravis, a chronic muscle weakness condition. 77 participants watched four short video lessons about building social support, managing emotions, and finding personal meaning. Re…

This study looked at whether adding folic acid and vitamin B12 to locally made cereal could help teenage girls in rural Ethiopia get the nutrients they need. The researchers measured vitamin levels, growth, thinking skills, and mood in 472 girls aged 13-19. The goal was to see if…

This small pilot study looked at how well blueberry flavonoids are absorbed and whether they can lower inflammation in older adults (65+) who have mild depressive symptoms. Six participants took either a standard or higher dose of blueberry powder, and researchers measured change…

This study looked at which combinations of support programs—New Hope, Elders Resilience, and Case Management—work best to reduce suicidal thoughts and build resilience in American Indian youth ages 10-29 who are at risk for suicide. Researchers tested different sequences of these…

This small study tested a type of talk therapy (RFCBT) that helps people break the cycle of repetitive negative thinking, called rumination. Researchers wanted to see if reducing rumination could also lower depressive symptoms and blood pressure in 9 low-income adults. The goal w…

This study looks at 128 children who were part of an early intervention program as infants. Now as teenagers, researchers are checking their brain activity, stress responses, and behavior to see if that early help made a difference. No new treatment is given—this is about underst…

This study tested two emotion regulation strategies—reconstrual (changing how you think about a situation) and repurposing (finding a new use for your feelings)—to see which better reduces sadness or anxiety in young adults aged 18 to 30. Over 200 participants completed online ta…

This study looked at whether community health workers visiting pregnant women at home in rural South Africa can improve health for both mothers and children. About 1,490 women took part, with some areas getting the home-visit program and others not. The program aimed to help with…

This study followed 1,290 adults with type 1 or type 2 diabetes for two years to see how mental health issues like depression, anxiety, and eating problems relate to blood sugar control. Participants completed surveys, interviews, and used smartphone apps and glucose monitors. Th…

This study tested a school-based program to help teenagers build psychological flexibility and resilience, aiming to reduce symptoms of depression, anxiety, and stress. 61 teens with mild to moderate distress took part in group sessions based on Acceptance and Commitment Therapy …

This study tested a program called RISE for young men leaving prison. The program provides trauma counseling and help finding a job and housing. Researchers wanted to see if this support would improve their mental health and stability, and lower the chance they would go back to p…