DEPRESSIVE SYMPTOMS

This study tested whether a physical activity program delivered by mail and website could improve the health of nearly 50,000 older women already in the Women's Health Initiative. The program included aerobic, balance, strength, and flexibility exercises, and encouraged reducing …

This completed study tested a program called RISE (Resiliency in Stressful Experiences) for young men ages 18-35 leaving state prisons in Florida. The program combines trauma counseling with practical help like housing and job support. Researchers measured whether participants ha…

This study tested different combinations of three programs—New Hope (coping skills), Elders Resilience (cultural strength), and Case Management—to see which best reduces suicidal thoughts and builds resilience in American Indian youth ages 10-29. The 304 participants were identif…

This study tested whether trained community health workers visiting pregnant women at home could improve health for both mothers and children in a rural area of South Africa. The program focused on supporting women with HIV, depression, or alcohol use, and on improving child grow…

This study tested an online mentoring program for transgender and gender minority youth aged 14-18. The program paired each teen with an adult transgender mentor for seven 90-minute group sessions focused on building social and emotional skills. The goal was to prevent problems l…

This study tested an online program called PROCARE-I+ designed to prevent anxiety and depression in teenagers who are at high risk. Thirty adolescents with early symptoms took part in the program, which included extra modules tailored to their needs. Results showed improvements i…

This study tested whether taking daily vitamin D or fish oil supplements could prevent depression in over 18,000 adults without significant mood issues at the start. Participants were followed for about 5 years. The results showed that neither supplement reduced the risk of devel…

This study tested a program called PRIME for older women with chronic pain and depression who also have physical disabilities. Nine women took part in nurse-led goal-setting visits and group therapy sessions focused on acceptance and commitment. The goal was to see if this combin…

This study tested a 4-week music program called 'Tuned In' for 133 Hong Kong teens struggling with low mood, anxiety, or loneliness. Participants were randomly assigned to start the program right away or wait 4 weeks. The program, led by a psychologist and music therapist, aimed …

This study tested a virtual support group called the Sister Circle for Black women aged 40 and older who have depressive symptoms. The program ran for 8 weeks and aimed to see if it was feasible and acceptable. Thirty women participated, and researchers measured how many complete…

This study tested a program called RESET, led by community health workers, to improve physical and mental well-being in older adults. Over 450 African American adults aged 50+ with symptoms like depression, anxiety, or chronic pain took part. The program included weekly group pho…

This study tested two ways to help adults with anxiety and depression become more aware of their emotions and learn to rethink them. One group used a smartwatch to track emotions in real time, while the other reflected on their day each evening. Over six weeks, both groups showed…

This study tested a computer-assisted cognitive behavioral therapy program called Raising Our Spirits Together (ROST) for rural adults with depressive symptoms. The program was delivered in small groups by local pastors, either online or in person at churches. Researchers compare…

This study looked at whether walking in nature reduces depressive symptoms more than walking in a city. 138 college students with mild to moderate depression were randomly assigned to take 30-minute walks twice a week for three weeks in either a natural or urban setting. Some nat…

This study tested a 6-week program that combines cognitive behavioral therapy, lifestyle tips, and communication skills for people caring for older adults in Hong Kong. The goal was to see if it could lower stress, depression, and anxiety in caregivers. 255 caregivers took part, …

This study tested a 4-week program called COPE (Coping Options for Parent Empowerment) for parents of teenagers in Spain. The program teaches emotional regulation and positive parenting skills in group sessions. Researchers measured changes in parents' anxiety, depression, stress…

This study tested a digital mental health program for adults with depressive symptoms. The program includes nine online modules covering topics like positive thinking, relaxation, and healthy habits. Researchers compared results between people with diagnosed mood disorders and th…

This small study tested whether taking aspirin and ketamine together by mouth can help people with treatment-resistant depression. Fifteen adults who had not gotten better with standard antidepressants received the combination alongside their usual medication. Researchers measure…

This study tested a school-based mental health program for teenagers with mild to moderate stress, anxiety, or depression. The program uses acceptance and commitment therapy (ACT) to help teens become more flexible and resilient. Sixty-one students took part in four group session…

This study looked at whether smelling lavender essential oil for 20 minutes before orthopedic surgery could lower anxiety, stress, and depression. 128 adults in Jordan took part, with half inhaling lavender oil and the other half receiving usual care. Results showed that the lave…

This study tested a 5-week online group program called Rare Group Problem Management Plus (PM+) for parents of children with rare diseases. The program teaches stress management and problem-solving skills to help reduce anxiety, depression, and distress. Eight parents participate…

This study tested two brief mental strategies—reconstrual and repurposing—to see which better reduces sadness and anxiety in 233 young adults aged 18-30. Participants read an emotional story, then practiced one of the strategies and rated their feelings. The goal is to find simpl…

This study tested a faith-based mobile app called PRAY.COM to see if it helps university students feel better mentally and emotionally. About 450 students used the app for at least 10 minutes each day over 8 weeks. Researchers checked if students liked the app and used it regular…

This study tested whether a smartphone-based cognitive behavioral therapy (CBT) program could help adults with psoriasis who also have depression symptoms. 30 participants used the app for 8 weeks with guidance from a coach. The goal was to see if people would engage with the pro…

This study tested a stepped-care telehealth program for cancer survivors living in rural areas who experience anxiety, depression, or sleep problems. Participants received either low-intensity check-ins or high-intensity phone therapy with a licensed therapist, depending on sympt…

This study tested a 12-week mobile phone program of daily reflection and meditation exercises for children with cancer and their families. The goal was to see if the program is practical and helpful for improving mental well-being and reducing anxiety and depression. Forty partic…

This study tested two ways to help adults with mild anxiety and depression in primary care. One was a 10-week group program, the other a single 50-minute session. Researchers wanted to see if the shorter option worked just as well. 136 people took part, and their symptoms were tr…

This study tested whether a special type of strength training (flywheel) is better than traditional strength training for improving mood, physical abilities, and thinking skills in older women who are not very active. Over 10 months, 64 women aged 60+ participated in one of the t…

This study tested whether daily smell training over 12 weeks can improve mood and smell perception in 150 people with mild depressive symptoms or major depression. Participants practiced smelling different odors each day. Researchers measured changes in smell ability and emotiona…

This small study tested a type of talk therapy called Rumination-Focused Cognitive Behavior Therapy (RFCBT) in 9 low-income adults who had both depressive symptoms and high blood pressure. The therapy aims to help people recognize and stop repetitive negative thoughts (rumination…

This study tested a 10-session therapy program delivered by phone or video to help adults with moderate-to-severe depression become more physically active. The goal was to see if the program was practical and liked by participants, and if it could reduce depressive symptoms. 65 a…

This study tested an online program to improve mental health in people with myasthenia gravis, a chronic muscle weakness condition. 77 patients completed a four-month program of short videos on Facebook about building social support, emotional awareness, and self-worth. Researche…

This study tested a culturally adapted internet-based cognitive behavioral therapy (iCBT) program for Arabic-speaking refugee and migrant youth aged 15–29 with mild to moderate mental health problems like depression, anxiety, and insomnia. 125 participants were randomly assigned …

This study tested whether a daily probiotic supplement (Lactobacillus reuteri) could lower stress, anxiety, and depressive symptoms in 150 adults aged 18-45 who reported feeling stressed. Participants took either the probiotic or a placebo for several weeks and completed surveys …

This pilot study tested a program called DAPPER for African American women aged 50 and older who have pain, depressive symptoms, and trouble moving around. Participants received 8 nurse visits at home to help manage their pain and mood. The study aimed to see if the program could…

This study tested a mobile web-based program to help caregivers of people with Alzheimer's disease reduce stress and depression. 184 caregivers aged 40 or older who provided at least 20 hours of in-home care per week and had mild depressive symptoms took part. The program aimed t…

This study tested two audio-based programs to help reduce depression symptoms in adults. 101 people with at least moderate depression were randomly assigned to listen to either a behavioral activation program or a self-monitoring program. Depression levels were checked before, du…

This study tested whether a 9-session group art program using Chinese calligraphy could reduce depressive symptoms and age-related self-stigma in older adults. 63 participants aged 60+ with mild depression risk were randomly assigned to the art program or usual care. The program …

This study tested whether a type of talk therapy called Cognitive Processing Therapy (CPT) can help adults who experienced the 2023 earthquakes in Turkey. Thirty-six participants with PTSD symptoms were randomly assigned to receive CPT or usual care. The goal was to see if CPT re…

This pilot study tested a culturally adapted form of cognitive behavioral therapy (CA-CBT) for adults who experienced the earthquakes in Türkiye and have high psychological distress. Sixty participants received 8 group sessions focusing on trauma education, emotion regulation, an…

This study tested whether a simple text-based game could help researchers learn how people make decisions when they feel depressed, anxious, or stressed. 350 adults played the game online for one week, and some received feedback during play. The goal was to see if the game could …

This study looked at 56 adults with fully remitted depression who wanted to stop their antidepressant. Researchers wanted to see how much of the withdrawal symptoms are caused by the drug itself versus the person's expectations. Participants were randomly assigned to either stop …

This study looks at 128 children who were part of an early intervention program in infancy and are now teenagers. Researchers measure brain activity, stress responses, and behaviors like risk-taking and mood to see if early help made a difference. No new treatment is given; this …

This study looked at whether adding folic acid and vitamin B12 to locally made cereals can improve the nutrition, thinking skills, and mood of teenage girls in rural Ethiopia. About 472 girls aged 13-19 took part. The goal was to see if small-scale food fortification can help pre…

This pilot study tested whether freeze-dried blueberry powder can boost flavonoid levels and reduce inflammation in older adults with mild depressive symptoms. Six participants aged 65 and older consumed either a standard or higher dose of blueberry powder for three days. Researc…

This completed study followed 1,290 adults with type 1 or type 2 diabetes for two years. Researchers tracked mental health issues like depression, anxiety, and eating problems alongside daily blood sugar levels using smartphone surveys and continuous glucose monitors. The goal wa…

This study looked at how first-year college students with mild-to-moderate depressive symptoms develop and cope with stress. 120 students participated, with some receiving weekly surveys and personalized feedback via text message. The goal was to see if this approach helps studen…