Sniff your way to a better mood? study tests smell training for depression

NCT ID NCT03605524

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether daily smell training over 12 weeks can improve mood and smell perception in 150 people with mild depressive symptoms or major depression. Participants practiced smelling different odors each day. Researchers measured changes in smell ability and emotional responses. The goal was to see if this simple, non-drug approach could help ease depression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sensory training (olfactory or visual)

What this could lead to

If it works, this could point toward a simple, drug-free way to ease depressive symptoms by retraining the sense of smell.

What could go wrong

This is a small, early-stage study with no placebo control, so results may not be conclusive. The effect on major depression is unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Anosmia Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UMR 1253 IBrain, University, Tours

    Tours, 37032, France

  • University Psychiatric Clinic, University hospital,Tours

    Tours, 37044, France

  • University health service, University ,Tours

    Tours, 37000, France