Brain zapping trial aims to brighten mood in Parkinson's

NCT ID NCT06467695

Recruiting now Symptom relief Sponsor: University of South Alabama Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive brain stimulation technique called MRI-guided transcranial direct current stimulation (tDCS) can reduce depression and apathy in people with Parkinson's disease. Forty participants will receive either real or sham stimulation, and researchers will measure changes in mood, brain activity, and memory. It is an early-stage trial focused on symptom relief, not a cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial direct current stimulation (tDCS) using a BIOPAC Stimsola device
What this could lead to: If it works, this could point toward a non-drug way to improve mood and thinking in people with Parkinson's disease.
What could go wrong: This is a small, early-stage study with only 40 people. The effects may be small or not last, and the sham group helps check if results are real.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSIVE SYMPTOMS PARKINSON DISEASE

Contacts and locations

Locations

University of South Alabama
RECRUITING

Mobile, Alabama, 36688, United States

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