Brain zapping trial aims to brighten mood in Parkinson's

NCT ID NCT06467695

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive brain stimulation technique called MRI-guided transcranial direct current stimulation (tDCS) can reduce depression and apathy in people with Parkinson's disease. Forty participants will receive either real or sham stimulation, and researchers will measure changes in mood, brain activity, and memory. It is an early-stage trial focused on symptom relief, not a cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial direct current stimulation (tDCS) using a BIOPAC Stimsola device

What this could lead to

If it works, this could point toward a non-drug way to improve mood and thinking in people with Parkinson's disease.

What could go wrong

This is a small, early-stage study with only 40 people. The effects may be small or not last, and the sham group helps check if results are real.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of South Alabama

    RECRUITING

    Mobile, Alabama, 36688, United States