Magnetic pulses to the brain may lift depression after concussion

NCT ID NCT05426967

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a non-invasive procedure called repetitive transcranial magnetic stimulation (rTMS) can safely reduce depressive symptoms in U.S. military service members and veterans who have had a concussion or mild traumatic brain injury. About 198 participants will receive either active rTMS or a sham (fake) treatment to compare effects. The goal is to find a better way to treat depression in this group without medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

repetitive transcranial magnetic stimulation (rTMS)

What this could lead to

If it works, this could offer a non-drug treatment option for depression after concussion, potentially improving quality of life for military members and veterans.

What could go wrong

This is an early adaptive trial with no phase designation, so results are uncertain. The sham group may also show improvement, and long-term benefits are not yet known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Brain Concussion Depression traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alexander T. Augusta Military Medical Center

    RECRUITING

    Fort Belvoir, Virginia, 22060, United States

    Contact

    Contact

  • VA Palo Alto Health Care System

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact

    Contact Email: •••••@•••••

  • William Beaumont Army Medical Center

    RECRUITING

    Fort Bliss, Texas, 79918, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact