MILD TRAUMATIC BRAIN INJURY

This study is testing a new device called TES HT100 that aims to quickly screen for brain injuries in adults coming to the emergency room with mild head trauma or certain neurological symptoms (like dizziness, confusion, or vision changes). The device takes about 5 minutes and wi…

This pilot study tests a new program called CRISP to help young adults aged 18-29 recover from concussion and mild traumatic brain injury. Participants must have had a concussion at least 2 weeks ago but less than 2 years ago, with new or worsening headaches. The study will see i…

This study tests whether special listening exercises can improve hearing for people who have had a mild traumatic brain injury (mTBI). Many with mTBI struggle to hear clearly in noisy environments or locate where sounds come from. Researchers will enroll 80 adults aged 18-55 with…

This study tests a personalized, noninvasive brain stimulation treatment (TMS) for people aged 18-65 with persistent symptoms after a mild concussion or brain injury, such as headache, dizziness, brain fog, or anxiety. Participants will receive either active or sham TMS over 10 s…

This study tests a technique called heart rate variability biofeedback, which uses breathing exercises to help people with long-lasting symptoms after a mild concussion. The goal is to reduce issues like headaches, dizziness, memory problems, and mood changes. The trial includes …

This study compares two types of talk therapy for insomnia in 160 active-duty military members who have had a mild traumatic brain injury and still have sleep and other symptoms for at least 3 months. One therapy is 6 sessions of Cognitive Behavioral Therapy for Insomnia (CBT-I),…

This study compares a standard home exercise program to a digital, game-like app for treating dizziness in adults who have had a mild traumatic brain injury. 68 participants will do balance and eye exercises for 4 weeks. Researchers want to see if the app version helps people fee…

This study is testing a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) to see if it can improve movement and thinking problems in children aged 10-15 who have had a mild traumatic brain injury or concussion. The researchers will use…

This study explores whether cognitive behavioral therapy for insomnia (CBT-I) can improve sleep, reduce brain injury symptoms, and help people with mild traumatic brain injury (mTBI) get back to their daily activities. Researchers will enroll 15 adults with mTBI and sleep problem…

This study tests two types of repetitive transcranial magnetic stimulation (rTMS) to see if they can safely reduce depression in U.S. military service members and veterans who have had a concussion or mild traumatic brain injury. About 198 participants will receive one of the two…

This early-phase study tests whether a non-invasive magnetic pulse treatment (iTBS) can safely reduce impulsivity and suicidal thoughts in veterans with mild traumatic brain injury. About 55 veterans will receive the treatment over two weeks. The goal is to gather initial safety …

This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce chronic headaches in people who had a mild traumatic brain injury. Researchers will track headache changes, sleep, and daily function in 60 ad…

This study looks at whether adding morning bright light therapy to cognitive training can improve thinking, daily function, and sleep in 144 veterans who have both mild traumatic brain injury and PTSD. Participants will receive either bright light or a placebo light along with co…

This study is testing a safe, home-based brain stimulation technique called RS-tDCS+ combined with cognitive training to improve attention in 160 active-duty service members and veterans who have had a mild traumatic brain injury. Participants will receive either real or sham sti…

This study tests whether daily growth hormone injections for 6 months can improve quality of life in veterans who have both mild traumatic brain injury (mTBI) and adult growth hormone deficiency (AGHD). About 172 veterans aged 21-55 will receive either the hormone or a placebo. T…

This study tests a new approach for people who still have thinking problems 3 to 12 months after a mild concussion. It combines a gentle, non-invasive brain stimulation technique called tDCS with computer-based cognitive training. Researchers want to see if this combo improves me…

This study tests whether combining a type of brain stimulation (called iTBS) with computer-based attention training can improve attention and daily life for people with mild traumatic brain injury (mTBI) and/or PTSD. Researchers will enroll 200 adults aged 18–80 who have had a mi…

This study tests a new, non-invasive brain stimulation technique called LIP-tES to help reduce light sensitivity in Veterans who have had a mild traumatic brain injury. About 36 participants will receive either real or sham stimulation and complete questionnaires and MRI scans to…

This study follows 250 adults aged 65 and older who have had a mild traumatic brain injury (TBI), often from a fall. Researchers will check their thinking, physical abilities, mood, and sleep at several points over one year. The goal is to learn how recovery happens and what fact…

This study tests whether a mild electrical pulse to a nerve in the head can improve blood flow and waste clearance in the brain. Researchers will measure changes in brain fluid movement using scans. The goal is to see if this approach could one day slow cognitive decline after mi…

This study looks at whether mild traumatic brain injuries (mTBIs) in Veterans increase the risk of dementia. Researchers will measure memory, brain waves, brain structure, and certain proteins in 800 participants. The goal is to find early signs of brain changes related to Alzhei…

This study aims to improve how mild traumatic brain injury (mTBI) is diagnosed and treated. Researchers will use advanced eye, balance, and reaction tests to better identify the injury and predict recovery. They will also test a new, low-risk therapy called passive neurosensory r…

This study uses powerful MRI scanners to look at the brains of 700 people, including those with conditions like multiple sclerosis, Alzheimer's, and Parkinson's, as well as healthy volunteers. The goal is to understand why some brains stay healthy while others develop disease. Re…