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New study aims to predict concussion recovery in children using symptoms and biology

NCT ID NCT05825027

Recruiting now Knowledge-focused Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study follows 500 children aged 8-17 who have had a concussion within the past week. Researchers track their symptoms, fatigue, social interactions, thinking skills, school needs, and biological markers like saliva inflammation and puberty hormones over a year. The goal is to build a model that identifies children at higher risk for persistent symptoms, so doctors and schools can create personalized plans to help them recover and return to learning and play.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a tool that helps doctors and schools identify children at risk for long-term concussion symptoms early, allowing for tailored support and faster recovery.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test any therapy. The model may not be accurate enough to use in practice, and results may not apply to all children.

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Conditions

The condition(s) this trial relates to.

Brain Concussion traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONCUSSION, BRAIN MILD TRAUMATIC BRAIN INJURY

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University Health System

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

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