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Could a probiotic pill ease stress and improve sleep?

NCT ID NCT07717385

Symptom relief Sponsor: Efforia, Inc Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether taking a daily probiotic supplement called Neuralli Mood for 90 days can help reduce stress, sleep problems, low mood, anxiety, and burnout in adults who experience these issues. Participants take two capsules each day and complete questionnaires before and after the 90-day period. The study is single-arm, meaning everyone gets the supplement and there is no placebo group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a daily probiotic supplement containing Lactobacillus plantarum PS128 and Lactobacillus paracasei PS23
What this could lead to
If it works, this could point toward a simple, non-prescription way to manage everyday stress and sleep problems.
What could go wrong
This is a small, early study with no placebo group, so results may be due to chance or the placebo effect. The supplement is not a treatment for any medical condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older and able to provide informed consent. * Generally healthy adult experiencing stress, occasional sleep disruption, low mood, anxiety symptoms, or work-related burnout. * Willing and able to take two capsules of Neuralli Mood daily for 90 days. * Willing and able to complete electronic baseline, follow-up, adherence, and safety assessments. * Has reliable access to the internet and an email-enabled device. Exclusion Criteria: * Pregnant or nursing. * Known allergy or hypersensitivity to Neuralli Mood, probiotics, or any product ingredient. * Severe or unstable gastrointestinal disease, including a condition for which probiotic use may be inappropriate. * Immunocompromised status or current immunosuppressive therapy. * Severe or unstable mood disorder, acute psychiatric symptoms, or a current risk of harm to self or others. * A clinically significant sleep disorder for which participation or changes in symptoms should be managed by a healthcare professional. * Cognitive impairment or another condition that prevents informed consent or reliable completion of study procedures. * History of a severe allergic reaction when the investigator determines probiotic use may present an unacceptable risk. * Use of a medication or presence of a medical condition for which a healthcare professional advises against probiotic supplementation. * Any other circumstance that, in the investigator's judgment, makes participation inappropriate or unsafe.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Burnout, Professional Burnout, Psychological Depression occupation-related stress disorder Parasomnias sleep disorder Stress, Psychological

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety symptoms Depressive symptoms Occupational burnout Psychological stress Sleep disturbance

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Efforia - Decentralized United States Study

    RECRUITING

    New York, New York, 10003, United States

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