New program aims to prevent depression and substance use in native communities

NCT ID NCT05836090

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program called Family Spirit Strengths (FSS) designed to help American Indian and Alaska Native mothers and caregivers cope with stress, build skills, and connect with their culture. About 188 participants will either receive FSS or a nutrition education program. Researchers will measure changes in mental health days and substance use over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Family Spirit Strengths (FSS) – a behavioral skills program

What this could lead to

If it works, this could provide an effective, culturally grounded way to prevent depression, anxiety, and substance use in Indigenous communities.

What could go wrong

This is a relatively small trial (188 participants) and compares the program to nutrition education, so results may not apply broadly. The program is behavioral, so effects may vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression substance abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins Center For Indigenous Health

    RECRUITING

    Shiprock, New Mexico, 87420, United States

    Contact Email: •••••@•••••

  • Johns Hopkins Center for Indigenous Health

    RECRUITING

    Chinle, Arizona, 86503, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pokagon Health Services

    RECRUITING

    Pokagon, Michigan, 49047, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••