New nerve block may cut opioid use after cancer surgery

NCT ID NCT07331129

Recruiting now Symptom relief Sponsor: National Cancer Institute, Egypt Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a nerve block called the transversalis fascia plane block can reduce pain after inguinal lymph node removal in cancer patients. The goal is to lower the need for strong painkillers like opioids, which can cause nausea, dizziness, and breathing problems. 90 adults will be randomly assigned to receive either the nerve block plus local anesthetic or just local anesthetic alone. Pain scores and opioid use will be tracked for 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transversalis fascia plane block (nerve block with local anesthetic)
What this could lead to: If it works, this could offer a better way to manage pain after groin lymph node surgery, reducing the need for opioids and their side effects.
What could go wrong: This is a small, early-phase study (90 people) testing a nerve block that may not work for everyone or could cause rare complications like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INGUINAL LYMPH NODES ENLARGED

Contacts and locations

Locations

National Cancer Institute Cairo University
RECRUITING

Cairo, 11796, Egypt

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