KIDNEY DISEASE

This study is testing whether a new smartphone app can help people with type 2 diabetes and reduced kidney function follow specific dietary advice. About 104 participants will use the app for six months to see if it helps them eat less salt and protein, which can protect kidney h…

This study is testing whether a program using an AI chatbot health coach and remote vital sign monitoring can help people better manage their interconnected chronic conditions. It aims to reduce serious health events like heart attacks, kidney failure, and hospitalizations. The t…

This study is testing if a treatment called Physiologic Insulin Resensitization (PIR) can help people with both advanced kidney disease and type 2 diabetes. It will compare PIR to standard care in 120 participants to see if it better protects kidney function and improves diabetes…

This study is testing if a medication called empagliflozin can help protect the kidneys and heart in people who have received a heart transplant. Researchers will enroll 200 veteran heart transplant recipients to take either the drug or a placebo for one year. The goal is to see …

This study aims to monitor the long-term heart and kidney health of women who experienced preeclampsia, HELLP syndrome, or kidney disease during pregnancy. It will follow 100 women to better understand their future health risks. The study is observational, meaning it collects hea…

This study is testing a 24-week lifestyle program called Inspire HER, designed specifically for Black women at risk for heart disease. The program provides health education, physical activity guidance, and social support resources. Researchers will compare the program's effective…

This study is testing an investigational drug called mezagitamab to see if it can help adults with IgA nephropathy, a condition where the immune system damages the kidneys. The main goal is to see if the drug reduces protein in the urine and helps protect long-term kidney functio…

This study is testing a special scale that measures heart and fluid signals to see if it can predict dangerous fluid overload in people using peritoneal dialysis for kidney failure. The goal is to give patients and doctors an early warning before a serious event happens, potentia…

This study aims to check the safety of the drug maribavir in adults who have had an organ or stem cell transplant, have a difficult-to-treat cytomegalovirus (CMV) infection, and also have severe kidney disease or kidney failure. Researchers will look at the existing medical recor…

This study aims to collect blood samples from 400 people who have received a kidney transplant. The goal is to use these samples to help develop a new, non-invasive blood test. This future test would check for signs of organ rejection or other problems without always needing a bi…

This study aims to understand the long-term health of children born to mothers who have had a solid organ transplant (like kidney, liver, or heart). Researchers want to see if these children have a higher risk of heart, kidney, or immune system problems later in life, possibly du…

This study aims to understand what makes certain immune proteins damage kidneys in IgA nephropathy, a common cause of kidney failure. Researchers will compare kidney tissue and blood samples from 150 adults with this disease to those with other kidney conditions. The goal is to f…

This online research study aims to understand how genes influence a person's risk of developing kidney disease. It is open to any adult living in the US, whether they have kidney disease or not. Participants complete a 20-minute health survey online and mail in a saliva sample us…

This is an early safety study to see how a new drug called Eloralintide moves through the body in people with severe kidney disease. Researchers will compare results from 28 participants—some with healthy kidneys and some with severe kidney impairment. The main goal is to underst…

This National Institutes of Health study aims to better understand kidney diseases caused by immune system problems. Researchers will observe 2,000 patients with conditions like nephrotic syndrome and lupus nephritis to learn about disease patterns, symptoms, and treatment respon…