KIDNEY DISEASE

This study tests whether an AI-powered health coach, along with a vital sign monitor, can help 300 adults with heart disease, diabetes, or kidney disease better manage their health. Participants will use a chatbot and tracking tools to improve key health numbers and reduce hospit…

This study tests a method called physiologic insulin resensitization (PIR) to see if it can improve kidney function in people with advanced chronic kidney disease and type 2 diabetes. About 120 adults will either receive PIR or standard care. Researchers will measure kidney healt…

This study tests a drug called mezagitamab in adults with IgA nephropathy, a kidney disease caused by protein buildup and inflammation. The main goal is to see if it lowers protein in urine (a sign of kidney damage) better than a placebo. About 347 participants will receive eithe…

This study tests a new treatment called AdiaVita, made from umbilical cord blood stem cells and exosomes with glutathione, for people with chronic kidney disease (CKD). About 100 adults aged 18 to 80 with moderate CKD will receive monthly IV infusions and a daily skin spray for t…

This study tests whether empagliflozin, a drug used for diabetes, can protect the kidneys and heart in people who have received a heart transplant. Heart transplant patients often face kidney and heart problems due to their condition and required medications. The trial will give …

This study tests a program called Inspire HER, designed to help Black women improve their heart health through education, physical activity, and social support. Researchers will enroll 90 Black women aged 30-79 with heart, kidney, or metabolic conditions in the Birmingham, AL are…

This study looks at a kidney disease called IgA nephropathy, which can lead to kidney failure. Researchers want to find special markers in the blood that could help diagnose the disease without needing a kidney biopsy. They will study 150 adults who need a kidney biopsy as part o…

This study tests whether a digital education program helps people with type 2 diabetes and chronic kidney disease stick to a low-sodium, low-protein diet. About 104 adults aged 18-74 will be followed for 6 months to see if their salt and protein intake changes. The goal is to imp…

This study looks at medical records of 10 adults who had a transplant and later got a CMV infection that was hard to treat, along with severe kidney disease or kidney failure (including those on dialysis). The goal is to see if the drug maribavir caused any side effects. No new t…

This study aims to learn more about kidney diseases caused by the immune system, such as nephrotic syndrome and lupus nephritis. Researchers will follow up to 2,000 adults and children to track symptoms, responses to treatment, and collect blood or urine samples. The goal is to b…

This study looks at how the drug eloralintide moves through the body in people with severe kidney disease or kidney failure compared to healthy people. About 28 adults will get a single shot under the skin and be monitored for about 14 weeks. The goal is to understand dosing and …

This study tests a special scale that measures heart signals to predict fluid overload in people with kidney disease on peritoneal dialysis. About 125 adults will use the scale at home to see if it can alert them before a serious event, like an emergency room visit. The goal is t…

This study aims to find genetic links to kidney disease by analyzing DNA from 50,000 adults across the US. You don't need to have kidney disease to join. Participation is online: fill out a 20-minute health survey and provide a saliva sample by mail. In return, you can get free g…

This study follows 100 women who had preeclampsia, HELLP syndrome, or kidney problems during pregnancy. Researchers will measure blood vessel stiffness and collect blood samples to understand long-term health risks. No new treatments are given; the goal is to learn how to better …

This study collects blood samples from 400 kidney transplant patients to help develop a non-invasive test that detects donor DNA in the blood. The test aims to monitor the health of the transplanted kidney without needing a biopsy. Participants must be 18 or older, have had a kid…

This study looks at the long-term health of children (16 and older) whose mothers had a solid organ transplant before pregnancy. Researchers want to see if these children have higher risks for heart or kidney problems, possibly due to the mother's anti-rejection medications. Abou…

This study collects health information, lifestyle details, and biological samples from up to 100,000 adults aged 18 to 90. The goal is to help researchers better understand conditions like lupus, celiac disease, and kidney disease, and to develop improved tests and treatments. Pa…

This study aims to understand how blood flow to the kidneys and liver changes in adults seriously injured in accidents. Researchers will use bedside ultrasound scans on 350 patients in intensive care to see if certain blood flow patterns can predict who develops kidney problems o…