New gel made from platelets shows promise for healing diabetic foot sores
NCT ID NCT06319287
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a gel called PEP-TISSEEL, made from platelet-derived particles and a natural sealant, on diabetic foot ulcers. 59 adults with type 1 or 2 diabetes and shallow foot sores were treated for 12 weeks. The goal was to see if the gel helps wounds close safely and faster than standard care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PEP-TISSEEL (a gel made from platelet-derived exosomes mixed with a fibrin sealant)
What this could lead to
If successful, this could offer a new topical treatment to help heal diabetic foot ulcers faster and reduce complications.
What could go wrong
This is an early Phase 2a trial with only 59 participants, so results may not apply widely. The treatment is applied topically, but risks like infection or poor healing remain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Professional Education & Research Institute (PERI)
Blue Ash, Ohio, 45242, United States