DIABETIC FOOT ULCER

This study tests a cream made from two plant extracts (Plectranthus amboinicus and Centella Asiatica) to see if it can completely heal diabetic foot ulcers. The trial includes 120 adults with type 1 or type 2 diabetes who have a moderate foot ulcer. Participants apply the cream o…

This study tests a new treatment called NOX1416 for people with diabetes who have foot ulcers that won't heal. About 40 adults will either get the gel plus standard care or standard care alone. The goal is to see if the gel is safe and helps wounds close completely.

This study was designed to see if placing a stent in a blocked leg vein could help heal diabetic foot ulcers in people with diabetes and leg swelling. Patients would have received standard wound care plus either a stent or no stent. However, the trial was withdrawn before any par…

This study tests whether adding special wound dressings (called CAMPs) to standard care helps close hard-to-heal diabetic foot and leg ulcers better than standard care alone. About 350 adults with these ulcers will be randomly assigned to receive either the extra dressings or usu…

This study tests a surgery called lymphovenous bypass for people with diabetic peripheral neuropathy, a common complication causing pain, numbness, and foot ulcers. The procedure aims to drain excess lymph fluid, which may reduce inflammation and nerve damage. Researchers will me…

This study tests whether adding a special amniotic membrane graft (BR-AM) to standard wound care helps heal diabetic foot ulcers better than standard care alone. About 72 adults with non-infected, non-healing ulcers will be randomly assigned to receive either BR-AM plus standard …

This trial tests a wearable insole system that monitors foot pressure, temperature, and movement, giving real-time alerts to help users shift weight and avoid injury. The study includes people with type 1 or 2 diabetes who have nerve damage and a recent history of healed foot ulc…

This study looks at whether a simple home exercise routine can help veterans who have recently healed from a diabetic foot ulcer. The goal is to improve their ability to walk and move safely without causing the ulcer to come back. The study involves 26 adults aged 50 and older wi…

This study was designed to test the safety and performance of the Avelle negative pressure wound therapy system on chronic wounds, including diabetic foot ulcers and venous leg ulcers. The device uses gentle suction to help wounds heal. However, the study was withdrawn before enr…

This early study tests a device called FITT on 20 people with hard-to-heal diabetic foot ulcers. The device combines several treatments to try to shrink the wound and ease pain. Researchers are checking if it is safe and if it improves quality of life.

This study tests a telemedicine platform that uses video-chat and interactive foot exercises to improve blood flow and healing in people with diabetic foot ulcers. Fifteen adults with diabetic foot ulcers will try the program at home. The goal is to see if the approach is accepta…

This study looks at a type of bacteria called Staphylococcus pettenkoferi, often found in diabetic foot ulcers. Researchers will analyze the DNA of 230 bacterial samples to see if certain strains are more harmful. The goal is to understand if this bacteria plays a role in making …