Herbal cream could heal diabetic foot wounds without surgery

NCT ID NCT06531512

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a cream made from two plant extracts (Plectranthus amboinicus and Centella Asiatica) to see if it can completely heal diabetic foot ulcers. The trial includes 120 adults with type 1 or type 2 diabetes who have a moderate foot ulcer. Participants apply the cream or a placebo daily for 16 weeks, and doctors check if the wound closes fully. The goal is to find a simple, topical treatment that avoids more invasive procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Xianglei Tangzu Gao (cream containing extracts of Plectranthus amboinicus and Centella Asiatica)

What this could lead to

If it works, this cream could offer a new, non-surgical way to heal diabetic foot ulcers, potentially reducing the risk of infection and amputation.

What could go wrong

This is an early-to-mid-stage trial with only 120 participants, so results may not apply to everyone. The cream may not heal ulcers faster than standard care, and skin irritation is possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Hospital of Jiangsu University

    Zhenjiang, Jiangsu, China

  • Huadong Hospital Affiliated to Fudan University

    Shanghai, China

  • Jiangmen Central Hospital

    Jiangmen, Guangdong, China

  • Longhua Hospital Shanghai University of Traditional Chinese Medicine

    Shanghai, China

  • Nanfang Hospital

    Guangzhou, China

  • Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

    Shanghai, China

  • Shanghai TCM Integrated Hospital

    Shanghai, China

  • Shenyang Seventh People's Hospital (Shenyang Hospital of Integrated Traditional Chinese and Western Medicine)

    Shenyang, Liaoning, China

  • Southern Medical University Third Hospital

    Guangzhou, China

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    Guangzhou, China

  • The First Affiliated Hospital of Henan University of Science & Technology

    Luoyang, Henan, China

  • The First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, China

  • The First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, Shaanxi, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China