Herbal cream could heal diabetic foot wounds without surgery
NCT ID NCT06531512
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a cream made from two plant extracts (Plectranthus amboinicus and Centella Asiatica) to see if it can completely heal diabetic foot ulcers. The trial includes 120 adults with type 1 or type 2 diabetes who have a moderate foot ulcer. Participants apply the cream or a placebo daily for 16 weeks, and doctors check if the wound closes fully. The goal is to find a simple, topical treatment that avoids more invasive procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Xianglei Tangzu Gao (cream containing extracts of Plectranthus amboinicus and Centella Asiatica)
- What this could lead to
- If it works, this cream could offer a new, non-surgical way to heal diabetic foot ulcers, potentially reducing the risk of infection and amputation.
- What could go wrong
- This is an early-to-mid-stage trial with only 120 participants, so results may not apply to everyone. The cream may not heal ulcers faster than standard care, and skin irritation is possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIABETIC FOOT ULCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Affiliated Hospital of Jiangsu University
Zhenjiang, Jiangsu, China
-
Huadong Hospital Affiliated to Fudan University
Shanghai, China
-
Jiangmen Central Hospital
Jiangmen, Guangdong, China
-
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Shanghai, China
-
Nanfang Hospital
Guangzhou, China
-
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China
-
Shanghai TCM Integrated Hospital
Shanghai, China
-
Shenyang Seventh People's Hospital (Shenyang Hospital of Integrated Traditional Chinese and Western Medicine)
Shenyang, Liaoning, China
-
Southern Medical University Third Hospital
Guangzhou, China
-
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, China
-
The First Affiliated Hospital of Henan University of Science & Technology
Luoyang, Henan, China
-
The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China
-
The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China
-
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Tailor-Made felt dressing speed up diabetic wound healing?
- Can a vacuum chamber help heal stubborn leg wounds?
- Could a simple exercise program speed healing of diabetic foot ulcers?
- Could stem cells from the placenta heal stubborn diabetic wounds?
- Smartphone app could let diabetic foot ulcer patients skip clinic visits for wound checks
- Wearable insoles warn of foot pressure to stop diabetic ulcers