DIABETIC FOOT ULCER

This early-stage study tests a topical spray called ELU42 on 15 adults with diabetic foot ulcers that have not healed for at least 4 weeks. The spray is applied three times a week for six weeks. The goal is to see if it is safe and helps shrink or close the wound.

This study tests whether using a special gait analysis system and custom shoe inserts can reduce the chance of diabetic foot ulcers coming back or leading to amputation. About 69 adults who have had a healed diabetic foot ulcer in the past will take part. Researchers will track h…

This study tests whether adding a special gel called Omeza Complete Matrix (OCM) to standard wound care helps diabetic foot ulcers heal faster. About 130 adults with diabetes and a foot ulcer that has lasted at least 4 weeks will be enrolled. Researchers will compare healing rate…

This study follows 50 people whose diabetic foot ulcers healed completely in a previous trial. Researchers will use photos and thermal scans to check if the ulcers stay closed over time. The goal is to see if a special amniotic membrane treatment helps prevent the ulcers from com…

This study tests whether a special graft made from donated placental tissue can help heal foot ulcers in people with diabetes that have not healed with standard care. About 60 adults with type 1 or 2 diabetes and a nonhealing foot ulcer will receive either the graft plus standard…

This study compares a wound vacuum (negative pressure therapy) to standard wound care for diabetic foot ulcers after surgery. Researchers want to see if the vacuum reduces the need for leg amputations and shortens hospital stays. About 50 adults with diabetic foot ulcers will tak…

This study tests whether adding a special dressing called EDX110 to standard wound care helps diabetic foot ulcers heal faster and more completely. About 298 adults with a non-healing foot ulcer will be randomly assigned to receive either standard care alone or standard care plus…

This study tests a gel called ENERGI-F703 on diabetic foot ulcers that haven't healed for at least 4 weeks. About 230 adults with diabetes will use either the gel or a placebo for 16 weeks. The main goal is to see if the gel helps the wound close completely and stay closed.

This study tests whether a gel called NeoThelium FT, used with standard wound care, helps close chronic diabetic foot ulcers better than standard care alone. About 132 adults with diabetes and a foot ulcer that has not healed for at least 4 weeks will take part. The main goal is …

This study compares two special skin grafts (PelloGraft and SanoGraft) to standard wound care for treating diabetic foot ulcers and venous leg ulcers. About 180 adults with these chronic wounds will be enrolled to see if the grafts help wounds close completely within 12 to 16 wee…

This study tests whether a special dehydrated human placenta tissue (dHPT) product, used alongside standard wound care, can help close diabetic foot ulcers that won't heal on their own. About 120 adults with diabetes and a foot ulcer will be randomly assigned to receive either st…

This study tests a gel called BB-101 on hard-to-heal foot and leg ulcers in people with diabetes. About 96 adults will receive either the gel or a placebo to see if it helps wounds shrink and close. The goal is to find a better way to manage these serious sores and prevent compli…

This study is testing a special skin graft called NeoThelium FT to see if it can help heal diabetic foot ulcers. Ten adults with diabetes and foot sores that are not infected will receive the graft. The main goal is to see if the wound closes completely and stays closed for at le…

This study tests a new wound dressing for diabetic foot ulcers. About 100 adults with diabetes will be randomly assigned to get either the new dressing or standard NHS care. The main goal is to see if the new dressing leads to complete wound healing within 12 weeks and reduces wo…

This study tests whether a special wound dressing made from human placental membrane can help heal diabetic foot ulcers and venous leg ulcers that won't close with standard care. About 50 adults with diabetes or vein problems will receive either the placental product plus usual c…

This study tests a device that combines light and magnetic pulses to help heal diabetic foot ulcers that have not closed with standard care. About 450 adults with these stubborn wounds will either get the real device or a fake (sham) device, plus usual wound care. The main goal i…

This study tests whether adding a special amniotic membrane graft (Orion™) to standard wound care helps diabetic foot ulcers heal faster in people aged 50-85. About 240 participants will be split into two groups: one gets standard care alone, the other gets standard care plus the…

This study is testing a soft, removable cast wrap designed to help foot ulcers heal in people with diabetes. Researchers want to see if the wrap is effective, safe, comfortable, and easy for patients to use. They will follow 100 adults with diabetic foot ulcers for up to 16 weeks…

This study tests a program called CARE-D-Foot-Nav, which provides a patient navigator to help adults with diabetic foot ulcers manage their care. The goal is to see if this extra support leads to more wounds healing completely within 20 weeks compared to usual care. The study wil…

This study tests three types of diabetic boots to see which helps people wear them as directed. Diabetic foot ulcers can lead to amputation if not treated properly. The smart boot uses a watch and phone to remind users to keep it on. Researchers hope better boot use will speed up…

This study is testing a device called FlowOx that uses gentle suction (intermittent negative pressure) to improve blood flow and heal wounds in people with diabetic foot ulcers. About 30 participants will use the device for one hour, twice a day for 12 weeks. The goal is to see i…

This study looks at medical records of 200 people with diabetic foot ulcers to find patterns in their health data. Researchers will check how blood test results relate to ulcer severity. The goal is to learn what factors lead to worse outcomes, so doctors can improve prevention a…

This study will enroll 5,000 adults with diabetes and open foot ulcers to test whether certain biomarkers can predict which wounds will heal. Researchers will collect blood, wound fluid, and tissue samples to measure healing, infections, and amputations over 52 weeks. The goal is…

This study follows 1000 adults with diabetic foot ulcers for up to 5 years to learn why they face higher risks of death and complications. Researchers will track health events like infections, amputations, and deaths to build a risk score. No new treatments are tested—the goal is…