Stem cell patch shows promise for diabetic foot wounds

NCT ID NCT04569409

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This Phase 3 study tested a sheet of donated stem cells (ALLO-ASC-DFU) on diabetic foot ulcers that have not healed for weeks. 104 adults with type 1 or type 2 diabetes and Wagner grade 2 ulcers were randomly assigned to receive the stem cell sheet or a placebo sheet. The main goal was to see if the stem cell sheet helped more wounds close completely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ALLO-ASC-DFU (a sheet of donated stem cells applied to the wound)

What this could lead to

If it works, this could provide a new treatment to help diabetic foot ulcers heal faster and more completely, reducing the risk of infection or amputation.

What could go wrong

This is a Phase 3 trial, but with only 104 participants, results may not apply to everyone. The treatment is a sheet applied to the wound, so it may not work for deeper or more complex ulcers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, Seoul, 05505, South Korea

  • Borame Medical Center

    Seoul, Seoul, 07061, South Korea

  • Bucheon ST. Mary's Hospital

    Gyeonggi-do, Bucheon, 14647, South Korea

  • Korea University Guro Hospital

    Seoul, Seoul, 08308, South Korea

  • Seoul National University Bundang Hospital

    Gyeonggi-do, Seongnam-si, 13620, South Korea