Can ozone gas help heal diabetic foot wounds?
NCT ID NCT05977309
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether applying ozone gas to diabetic foot ulcers helps them heal faster. 430 people with diabetic foot ulcers received either standard wound care plus ozone therapy or standard care alone. The treatment was given every three days for a total of eight sessions. The study measured wound size, skin oxygen levels, and infection to see if ozone made a difference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- topical ozone therapy (device)
- What this could lead to
- If it works, this could offer a simple, low-cost addition to standard wound care for diabetic foot ulcers.
- What could go wrong
- This is a single completed trial with mixed evidence. Ozone therapy may not speed healing and could cause skin irritation or other side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Griya Husada Clinic
Kediri, Indonesia, 64118, Indonesia
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