Needle vs. needle: botox and filler go Head-to-Head for gummy smile fix
NCT ID NCT07715331
First seen Jul 20, 2026 · Last updated Jul 22, 2026 · Updated 2 times
Summary
This trial tests two non-surgical injectable treatments for a gummy smile, where too much gum shows when smiling. Twenty adults with a gummy smile of 3 mm or more received either botulinum toxin (Botox) or a hyaluronic acid filler. The study measures how much the gum exposure is reduced and how satisfied patients are with their smile over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- botulinum toxin type A (Refinex) or cross-linked hyaluronic acid filler (Juvéderm Voluma with lidocaine)
- What this could lead to
- If successful, this could provide a non-surgical, office-based option for people bothered by a gummy smile, improving confidence and quality of life.
- What could go wrong
- This is a small, early-stage trial with only 20 participants, so results may not apply to everyone. The effects of botulinum toxin may wear off within months, requiring repeat treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of Dental Medicine for Girls, Al-Azhar University
Cairo, Cairo Governorate, Egypt
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