Which procedure wins for kidney stones in oddly shaped kidneys?

NCT ID NCT05240170

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial compares two ways to treat kidney stones in people whose kidneys are shaped or positioned abnormally from birth. One method, retrograde intrarenal surgery (RIRS), uses a thin scope passed through the urinary tract to break up stones with a laser. The other, shockwave lithotripsy (SWL), sends shock waves from outside the body to shatter stones. The study will see which approach clears more stones completely, with fewer complications and less need for repeat treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Two procedures are compared: retrograde intrarenal surgery (RIRS), using a flexible scope and laser to break up stones, and extracorporeal shockwave lithotripsy (SWL), which uses shock waves from outside the body to fragment stones.
What this could lead to
If RIRS proves more effective, it could become the preferred treatment for kidney stones in people with congenital kidney anomalies, improving stone clearance and reducing the need for repeat procedures.
What could go wrong
This is a single-center study, and results may not apply to all patients. RIRS is more invasive and carries risks like bleeding or infection, while SWL may be less effective for certain stone types.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Urology Department, Al-Azhar University Hospital

    Cairo, Egypt

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