Sound waves smash kidney stones without surgery

NCT ID NCT05701098

Completed Disease control Sponsor: SonoMotion Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a device called Break Wave™ that uses focused ultrasound waves to break kidney stones into tiny pieces that can pass naturally. 64 adults with upper urinary tract stones (4-10 mm) received the treatment. The goal was to see if the device is safe and effective at fragmenting stones, with follow-up imaging at 10 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Break Wave device (ultrasound waves to break kidney stones)
What this could lead to: If successful, this could offer a non-surgical option to break kidney stones, reducing the need for more invasive procedures.
What could go wrong: This is a small, completed trial with only 64 participants. The device may not work for all stone types or sizes, and there are risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis Urinary Calculi urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KIDNEY CALCULI KIDNEY STONE NEPHROLITH NEPHROLITHIASIS RENAL CALCULI URINARY CALCULI UROLITHIASIS

Contacts and locations

Locations

Kaiser Permanente

Santa Clara, California, 95051, United States
Lehigh Valley Health Network

Allentown, Pennsylvania, 18103, United States
Northwestern Medicine

Chicago, Illinois, 60611, United States
St. Michael's Hospital, University of Toronto

Toronto, Ontario, M5C 2T2, Canada
University of Alberta

Edmonton, Alberta, T6G 1Z1, Canada
University of British Columbia

Vancouver, British Columbia, Canada
University of California - San Francisco

San Francisco, California, 94143, United States
University of California- San Diego

San Diego, California, 92037, United States
University of Washington

Seattle, Washington, 98195, United States
Vanderbilt University

Nashville, Tennessee, 37232, United States

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