NEPHROLITHIASIS

This study looks at the best time to use shock wave therapy (ESWL) to break up small leftover kidney stones after surgery. About 476 adults with stones 15 mm or smaller will be split into two groups: one gets ESWL within 1-2 weeks after surgery, the other waits 3-4 weeks. The goa…

This study compares standard kidney stone surgery (using a scope and laser) to the same surgery plus a special hydrogel that captures tiny stone fragments. The goal is to see if the gel helps remove more stone pieces, which could lower the chance of stones coming back. About 120 …

This study compares two standard surgical methods for removing kidney stones: mini-PCNL (a small incision in the back) and flexible ureteroscopy with a suction tube. The goal is to see which method leaves fewer stone fragments behind. About 80 adults with kidney stones between 1 …

This study compares two treatments for kidney stones that are 1 to 2 centimeters in size: shock wave therapy from outside the body (ESWL) and laser surgery through a thin tube (RIRS). About 98 adults will take part, and researchers will track how completely the stones are cleared…

This study compares three different single-use flexible ureteroscopes used to remove kidney stones. Researchers will look at cost, how long surgery takes, complications, and how well the stones are cleared. The trial involves 180 adults aged 18 to 60 with kidney stones smaller th…

This study compares two FDA-approved lasers (Holmium:YAG with MOSES and thulium fiber) for breaking large kidney stones during a minimally invasive surgery called mini-PCNL. About 150 adults with stones larger than 15mm will be randomly assigned to one laser, both using a suction…

This study tests a simple change during kidney stone surgery: after removing the stone, doctors suction the kidney to make it collapse. The goal is to see if this lowers pain and infection risk after surgery. About 90 adults with kidney stones will take part, and half will get th…

This study looks at whether a 21-day spa program, including mineral water baths and exercise, can help people with chronic kidney and urinary tract problems. Researchers will check 150 adults (ages 40-70) before and after treatment using blood tests, urine tests, and quality-of-l…

This study tests if placing a numbing medicine (bupivacaine) into the bladder after kidney stone surgery can lower pain and improve recovery. About 116 adults having ureteroscopy with stenting will receive either the medicine or a saltwater placebo. The goal is to see if this sim…

This study is testing whether a blood test can help doctors predict which patients might develop an infection or serious inflammation after kidney stone surgery. Researchers will measure a substance called endotoxin in the blood before and after surgery. The goal is to create a r…

This study looks at whether giving surgeons live information about pressure inside the kidney during a stone-removal procedure changes the way they work. About 80 adults with large kidney stones will take part. The main goal is to see if the pressure data improves the surgeon's n…