NEPHROLITHIASIS
Clinical trials for NEPHROLITHIASIS explained in plain language.
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Sound waves zap kidney stones in new device trial
Disease control CompletedThis study tested a new device called Break Wave that uses sound waves to break kidney stones into tiny pieces. 64 people with upper urinary tract stones took part. The goal was to see if the device is safe and effective at breaking stones so they can pass naturally.
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: SonoMotion • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Laser vs Mini-Surgery: which is better for kidney stones?
Disease control CompletedThis study looked at 60 adults with kidney stones between 2 and 3 cm. It compared a newer, less invasive laser procedure (RIRS) with a mini-surgery (MiniPCNL) to see which removes stones more completely and safely. The goal is to find the best treatment with fewer complications.
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Necmettin Erbakan University • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New study finds best way to zap kidney stones in kids
Disease control CompletedThis study looked at 180 children aged 6 to 12 with hard kidney stones (1-2 cm) in the lower part of the kidney. It compared two surgeries: mini percutaneous nephrolithotomy (a small tube through the back) and flexible ureteroscopy (a scope through the urinary tract). The goal wa…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New study tests best strategy to stop kidney stones
Disease control CompletedThis study tested two approaches to prevent kidney stones in adults who have had at least two stones in the past five years. One group received a personalized prevention plan based on their urine test results, while the other group followed a standard diet and medication plan. Th…
Matched conditions: NEPHROLITHIASIS
Phase: PHASE4 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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New study compares three kidney stone removal methods – which works best?
Disease control CompletedThis study looked at 90 adults with kidney stones up to 2 centimeters to see which surgical technique works best. Doctors compared three methods: using a traditional tube, a tube with suction, or no tube at all during a scope procedure. The goal was to find the safest and most ef…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated May 05, 2026 11:55 UTC
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New laser microscope may replace biopsies for urinary tract tumors
Diagnosis CompletedThis study tested whether a laser microscope used during a kidney-ureter scope procedure can tell normal tissue from tumors in the upper urinary tract. 29 adults with blood in urine, kidney stones, or urinary tract cancer took part. The goal was to see if this technique could red…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Lille Catholic University • Aim: Diagnosis
Last updated May 12, 2026 13:41 UTC
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Nerve block eases pain after kidney stone procedure
Symptom relief CompletedThis study tested whether a special nerve block called the erector spinae plane (ESP) block can improve pain relief after flexible ureteroscopy (URS) surgery for kidney stones. Seventy adults were randomly assigned to receive either the ESP block plus standard pain care or standa…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Namik Kemal University • Aim: Symptom relief
Last updated May 17, 2026 06:58 UTC
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New suction tool may speed up kidney stone surgery
Symptom relief CompletedThis study tested whether a new flexible access sheath with suction can make kidney stone surgery faster and safer compared to a standard sheath. Fifty adults with kidney stones 10 mm or larger were randomly assigned to one of the two sheaths during a minimally invasive procedure…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Barzilai Medical Center • Aim: Symptom relief
Last updated May 17, 2026 06:47 UTC
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New suction tool may make kidney stone surgery safer and more effective
Symptom relief CompletedThis study tested two different devices used during surgery to remove kidney stones up to 20 mm. One is a traditional tube that lets fluid and stone fragments flow out passively, and the other is a newer tube that uses suction to actively pull out fragments and reduce pressure in…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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No-Tube kidney stone surgery may mean less pain for kids
Symptom relief CompletedThis study looked at 640 children aged 6 to 18 with large kidney stones. It compared the standard surgery that leaves a drainage tube in the kidney to a newer 'tubeless' method that skips the tube. The goal was to see if the tubeless approach is just as safe and leads to less pai…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Lady Reading Hospital, Pakistan • Aim: Symptom relief
Last updated May 05, 2026 11:53 UTC
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Pill before surgery may help kidney stone removal
Symptom relief CompletedThis study tested whether taking tadalafil (Cialis) or tamsulosin (Flomax) before kidney stone surgery helps doctors place a larger tube into the ureter. A larger tube can make stone removal easier and safer. 220 adults having kidney stone surgery were randomly assigned to receiv…
Matched conditions: NEPHROLITHIASIS
Phase: PHASE4 • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Apr 24, 2026 16:18 UTC
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Does anesthesia choice affect inflammation after kidney stone surgery?
Knowledge-focused CompletedThis study looked at 90 adults having kidney stone surgery to see if the type of anesthesia (spinal vs general) changes inflammation levels. Researchers used standard blood test results from before and after surgery, without any extra blood draws. The goal was to learn more about…
Matched conditions: NEPHROLITHIASIS
Sponsor: Sevim Şenol Karataş • Aim: Knowledge-focused
Last updated May 17, 2026 06:50 UTC
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Anesthesia flow may affect eye pressure during kidney stone procedure
Knowledge-focused CompletedThis study looked at how different types of anesthesia affect eye pressure and the optic nerve during kidney stone surgery. Sixty adults having the surgery were randomly assigned to receive either minimal low-flow or high-flow anesthesia. The goal was to see which method is safer…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Elazıg Fethi Sekin Sehir Hastanesi • Aim: Knowledge-focused
Last updated May 17, 2026 06:46 UTC
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Kidney stone study uncovers secrets of drinking more water
Knowledge-focused CompletedThis study looked at how a 3-month program using a smart water bottle and phone app helps people who have had kidney stones drink more fluids. Researchers wanted to understand what makes people stick with healthy habits. 172 adults with a past kidney stone diagnosis took part. Th…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC