NEPHROLITHIASIS
Clinical trials for NEPHROLITHIASIS explained in plain language.
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New study tests best strategy to stop kidney stones
Disease control CompletedThis study looked at two different approaches to prevent kidney stones in adults who have had at least two stones in the past five years. One approach used diet and medication based on each person's test results, while the other used a standard one-size-fits-all plan. The goal wa…
Matched conditions: NEPHROLITHIASIS
Phase: PHASE4 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Sound waves smash kidney stones without surgery
Disease control CompletedThis study tested a device called Break Wave™ that uses focused ultrasound waves to break kidney stones into tiny pieces that can pass naturally. 64 adults with upper urinary tract stones (4-10 mm) received the treatment. The goal was to see if the device is safe and effective at…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: SonoMotion • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Laser vs. Mini-Surgery: which is better for kidney stones?
Disease control CompletedThis study compared two ways to remove kidney stones that are 2-3 cm in size. One method uses a laser and a special suction tube through a scope in the urinary tract. The other is a mini-surgery that makes a small cut in the back. Researchers looked at how well each method cleare…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Necmettin Erbakan University • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New study tests better infection prevention for kids after kidney stone surgery
Disease control CompletedThis study looked at 140 children aged 4 to 14 who had kidney stones and underwent a procedure called flexible ureteroscopy. Researchers compared giving antibiotics before surgery versus using extra preventive steps to see which better reduces urinary tract infections after the p…
Matched conditions: NEPHROLITHIASIS
Phase: PHASE2, PHASE3 • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New laser microscope could spot urinary tract tumors without needles
Diagnosis CompletedThis study tested whether a laser confocal microscope, used during a kidney-ureter scope procedure, can tell the difference between normal and cancerous tissue in the upper urinary tract. 29 adults with conditions like blood in urine, kidney stones, or urinary tract cancer took p…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Lille Catholic University • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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New suction tool may speed up kidney stone surgery
Symptom relief CompletedThis study tested a new type of ureteral access sheath with a flexible tip and built-in suction during kidney stone surgery. Fifty adults with kidney stones 10 mm or larger were randomly assigned to receive either the new suction sheath or a standard sheath. The main goal was to …
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Barzilai Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Which painkiller dose works best after kidney stone surgery?
Symptom relief CompletedThis study looked at two different strengths of the numbing medicine bupivacaine used in a nerve block for pain after kidney stone surgery. Sixty adults having the surgery received either a 0.25% or 0.375% concentration. Researchers measured their pain levels, how much extra pain…
Matched conditions: NEPHROLITHIASIS
Sponsor: Ankara Education and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New pain combo could ease kidney stone recovery
Symptom relief CompletedThis study tested whether adding hyaluronidase to a common numbing drug (bupivacaine) improves pain control after kidney stone surgery. 100 adults undergoing the procedure received an ultrasound-guided nerve block with or without hyaluronidase. The goal was to see if the combinat…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Kasr El Aini Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New nerve block slashes opioid use in kidney stone surgery
Symptom relief CompletedThis study tested a nerve block called anterior quadratus lumborum block in 54 adults having kidney stone surgery. The block reduced pain and the amount of strong painkillers (opioids) needed during and after surgery. It did not affect nausea or overall recovery quality at 24 hou…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Zonguldak Bulent Ecevit University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Nerve block eases pain after kidney stone procedure
Symptom relief CompletedThis study tested whether a special nerve block called the erector spinae plane (ESP) block can improve pain control after flexible ureteroscopy, a common surgery for kidney stones. 70 adults were randomly assigned to receive either the ESP block plus standard pain care or standa…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Namik Kemal University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Study tests two drugs to improve kidney stone removal
Symptom relief CompletedThis study tested whether giving tadalafil (Cialis) and/or tamsulosin (Flomax) before kidney stone surgery helps doctors place a larger tube into the ureter, which can make the procedure safer and more effective. 220 adults undergoing surgery for kidney stones were randomly assig…
Matched conditions: NEPHROLITHIASIS
Phase: PHASE4 • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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New suction device may improve kidney stone removal
Symptom relief CompletedThis study tested two different tools used during surgery to remove kidney stones up to 20 mm. One is a traditional tube that lets fluid and stone pieces flow out, and the other is a newer tube that uses suction to actively pull out stone fragments. The goal was to see which tool…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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New study finds best method to zap kidney stones in kids
Symptom relief CompletedThis study looked at 180 children aged 6-12 with hard kidney stones (1-2 cm). It compared two procedures: mini-PCNL (a small back incision) and flexible ureteroscopy (a tube through the urinary tract). The goal was to see which method removes stones more completely and safely. Re…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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New study reveals best technique for kidney stone removal
Symptom relief CompletedThis study tested three different methods for removing kidney stones up to 2 centimeters in size. All methods use a flexible scope through the urinary tract, but one uses a traditional tube, another uses a tube with suction, and the third uses no tube at all. Researchers measured…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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No tube, less pain? new study tests simpler kidney stone surgery for kids
Symptom relief CompletedThis study compared two surgical techniques for removing large kidney stones in children aged 6 to 18. The traditional method leaves a temporary drainage tube in the kidney, while the newer 'tubeless' method skips that tube. Researchers wanted to see if the tubeless approach redu…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Lady Reading Hospital, Pakistan • Aim: Symptom relief
Last updated Jun 26, 2026 18:53 UTC
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Spinal vs. general anesthesia: which is better for kidney stone surgery?
Knowledge-focused CompletedThis study looked at 90 adults having kidney stone surgery to see if the type of anesthesia—spinal or general—affects the body's inflammation response. Researchers measured blood markers before and after surgery. The goal is to learn which method might lead to less inflammation a…
Matched conditions: NEPHROLITHIASIS
Sponsor: Elazıg Fethi Sekin Sehir Hastanesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Suction vs. no suction: which is safer for kidney stone surgery?
Knowledge-focused CompletedThis study looked at pressure inside the kidney during surgery to remove kidney stones. Twenty-one adults had the procedure with either a suction or a non-suction tube. The goal was to see which method keeps pressure lower, which could make surgery safer and help clear more stone…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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App and bottle combo aims to flush away kidney stones
Knowledge-focused CompletedThis study tested a system called sipIT that uses a smart water bottle and phone app to track fluid intake and send reminders. The goal was to see if it helps kidney stone patients form a habit of drinking more fluids. 172 adults with a recent kidney stone diagnosis used the syst…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Lying on your back or belly? study tests lung risk in kidney stone surgery
Knowledge-focused CompletedThis study looked at 200 adults having kidney stone surgery to see if lying on their back versus their belly changes the risk of lung problems after surgery. Researchers measured lung 'mechanical power' during surgery and tracked complications. The goal is to find the safest posi…
Matched conditions: NEPHROLITHIASIS
Sponsor: TC Erciyes University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Does anesthesia choice affect inflammation after kidney stone surgery?
Knowledge-focused CompletedThis study looked at 90 adults having kidney stone surgery to see if the type of anesthesia (spinal or general) changes inflammation levels after the procedure. Researchers used standard blood tests taken before and after surgery to measure inflammation. No extra blood draws or t…
Matched conditions: NEPHROLITHIASIS
Sponsor: Sevim Şenol Karataş • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Anesthesia technique may affect eye pressure during kidney stone procedure
Knowledge-focused CompletedThis completed study looked at how two different anesthesia gas flows affect eye pressure and optic nerve during kidney stone surgery. Sixty adults having the procedure were randomly assigned to receive either minimal low-flow or high-flow anesthesia. Researchers measured eye pre…
Matched conditions: NEPHROLITHIASIS
Phase: NA • Sponsor: Elazıg Fethi Sekin Sehir Hastanesi • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:22 UTC