New pain block could cut opioid use in kidney stone surgery

NCT ID NCT07457983

Completed Symptom relief Sponsor: Fadime Tosun Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 21, 2026 · Updated 3 times

Summary

This study tests whether an erector spinae plane block, a type of nerve block, can reduce pain and the need for opioid painkillers after percutaneous nephrolithotomy, a surgery to remove large kidney stones. Sixty adults scheduled for this surgery will receive either the block plus standard anesthesia or standard anesthesia alone. Researchers will measure pain scores and total opioid use in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: erector spinae plane block with bupivacaine
What this could lead to: If it works, this could offer a safer way to manage pain after kidney stone surgery, reducing the need for opioids.
What could go wrong: This is a small, early-stage trial with only 60 participants. The block may not provide significant pain relief, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ERECTOR SPINAE PLANE (ESP) BLOCK NEPHROLITHIASIS PERCUTANEOUS NEPHROLITHOTOMY (PCNL) RENAL CALCULI

Contacts and locations

Locations

Adıyaman University Faculty of Medicine Anesthesiology and Reanimation

Adıyaman, Turkey (Türkiye)

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