Which painkiller dose works best after kidney stone surgery?

NCT ID NCT07653230

Completed Symptom relief Sponsor: Ankara Education and Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at two different strengths of the numbing medicine bupivacaine used in a nerve block for pain after kidney stone surgery. Sixty adults having the surgery received either a 0.25% or 0.375% concentration. Researchers measured their pain levels, how much extra pain medicine they needed, and changes in blood inflammation markers. The goal was to see if one concentration provides better pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine
What this could lead to: If successful, this could help doctors choose the best dose of bupivacaine for pain relief after kidney stone surgery, potentially reducing pain and opioid use.
What could go wrong: This is a small, completed study with only 60 participants. The results may not apply to all patients, and the two concentrations may show little difference in pain control.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEPHROLITHIASIS PERCUTANEOUS NEPHROLITHOTOMY (PNL)

Contacts and locations

Locations

Ankara Training and Research Hospital

Ankara, Mamak, 06420, Turkey (Türkiye)

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