NEPHROLITHIASIS

This study compares standard kidney stone surgery (using a scope and laser) to the same surgery plus a special hydrogel that captures tiny stone fragments. The goal is to see if the gel helps remove more stone pieces, which could lower the chance of stones coming back. About 120 …

This study compares two FDA-approved lasers (Holmium:YAG with MOSES and thulium fiber) for breaking large kidney stones during a minimally invasive surgery called mini-PCNL. About 150 adults with stones larger than 15mm will be randomly assigned to one laser, both using a suction…

This study looks at the best time to use shock waves to break up small kidney stones left behind after surgery. About 476 adults with leftover stones will be split into two groups: one gets treatment within 1-2 weeks after surgery, the other waits 3-4 weeks. The goal is to see wh…

This study compares two common procedures for removing kidney stones: mini-PCNL (a small incision in the back) and flexible ureteroscopy with a special suction tube. About 80 adults with stones 1-3 cm will be randomly assigned to one procedure. The main goal is to see which metho…

This study tests a simple change during kidney stone surgery: after removing the stone, doctors suction the kidney to make it collapse. The goal is to see if this lowers pain and infection risk after surgery. About 90 adults with kidney stones will take part, and half will get th…

This study looks at whether a 21-day spa program, including mineral water baths and exercise, can help people with chronic kidney and urinary tract problems. Researchers will check 150 adults (ages 40-70) before and after treatment using blood tests, urine tests, and quality-of-l…

This study tests if placing a numbing medicine (bupivacaine) into the bladder after kidney stone surgery can lower pain and improve recovery. About 116 adults having ureteroscopy with stenting will receive either the medicine or a saltwater placebo. The goal is to see if this sim…

This study compares three different single-use flexible ureteroscopes used to remove kidney stones. Researchers want to see which one is most cost-effective, has the fewest complications, and clears the most stones. The trial involves 180 adults aged 18 to 60 with kidney stones s…

This study compares two common treatments for kidney stones that are 1 to 2 centimeters in size: shock wave therapy (ESWL) and laser surgery (RIRS). About 98 adults with a single kidney stone will receive one of the two treatments and be followed for 28 days. The goal is to see w…

This study looks at whether giving surgeons live information about pressure inside the kidney during a stone-removal procedure changes the way they work. About 80 adults with large kidney stones will take part. The main goal is to see if the pressure data improves the surgeon's n…

This study looks at whether a blood test that measures endotoxin levels can help predict infections after a type of kidney stone surgery called percutaneous nephrolithotomy (PCNL). Researchers will test blood samples from 150 adults before and after surgery to see if higher endot…