New nerve block may cut opioid use after kidney stone surgery

NCT ID NCT05024344

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a nerve block called an erector spinae plane (ESP) block can reduce pain and the need for opioid painkillers after percutaneous nephrolithotomy, a surgery to remove large kidney stones. About 128 adults having this surgery will be randomly assigned to receive either the ESP block or a placebo (saline) injection. The main goal is to see if the ESP block lowers opioid use in the first 24 hours after surgery and improves pain scores.

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Conditions

The condition(s) this trial relates to.

nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Tennessee Medical Center

    RECRUITING

    Knoxville, Tennessee, 37920, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••