New hope for kidney stone sufferers: drug and diet combo tested in major trial

NCT ID NCT06653738

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 4 times

Summary

This study tests two approaches to prevent kidney stones from coming back in people who have had them before. One approach uses a daily pill called empagliflozin (a diabetes drug) and the other gives personalized diet advice based on urine tests. The trial will involve 400 adults with calcium-based kidney stones and will last 3 years.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Charité University Medicine Berlin

    NOT_YET_RECRUITING

    Berlin, 10117, Germany

  • Hôpital Européen Georges Pompidou

    NOT_YET_RECRUITING

    Paris, 75908, France

  • Hôpital Tenon

    NOT_YET_RECRUITING

    Paris, 75020, France

  • Inselspital Bern

    RECRUITING

    Bern, 3010, Switzerland

  • Kantonsspital Aarau

    NOT_YET_RECRUITING

    Aarau, 5001, Switzerland

  • Kantonsspital Baden

    NOT_YET_RECRUITING

    Baden, 5404, Switzerland

  • Kantonsspital Chur

    NOT_YET_RECRUITING

    Chur, 7000, Switzerland

  • Kantonsspital Fribourg

    NOT_YET_RECRUITING

    Fribourg, 1708, Switzerland

  • Kantonsspital Luzern

    NOT_YET_RECRUITING

    Lucerne, 6016, Switzerland

  • Kantonsspital Neuchâtel

    NOT_YET_RECRUITING

    Neuchâtel, 2000, Switzerland

  • Kantonsspital Olten

    NOT_YET_RECRUITING

    Olten, 4600, Switzerland

  • Kantonsspital Sion

    NOT_YET_RECRUITING

    Sion, 1950, Switzerland

  • Kantonsspital St. Gallen

    NOT_YET_RECRUITING

    Sankt Gallen, 9007, Switzerland

  • Lausanne University Hospital (CHUV)

    NOT_YET_RECRUITING

    Lausanne, 1011, Switzerland

  • Regionalspital Lugano

    NOT_YET_RECRUITING

    Lugano, 6900, Switzerland

  • University Hospital Amiens-Picardie

    NOT_YET_RECRUITING

    Amiens, 80054, France

  • University Hospital Basel

    NOT_YET_RECRUITING

    Basel, 4031, Switzerland

  • University Hospital Geneva (HUG)

    NOT_YET_RECRUITING

    Geneva, 1211, Switzerland

  • Università della Campania "Luigi Vanvitelli"

    NOT_YET_RECRUITING

    Naples, 80131, Italy

  • Universitätsspital Zürich

    NOT_YET_RECRUITING

    Zurich, 8091, Switzerland

  • Verona University Hospital

    NOT_YET_RECRUITING

    Verona, 37134, Italy

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