Can a gut bug beat kidney stones?
NCT ID NCT06330246
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving people a live gut bacterium called Oxalobacter formigenes can lower the amount of oxalate in their urine. High urinary oxalate is a major risk factor for calcium oxalate kidney stones. Forty adults with a history of such stones who lack this bacterium will take it by mouth, then follow controlled diets to measure changes in oxalate levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
live Oxalobacter formigenes bacteria
What this could lead to
If it works, this could point toward a natural way to reduce kidney stone risk by restoring a helpful gut bacterium.
What could go wrong
This is a small, early-stage study with only 40 participants. It tests a short-term effect, and long-term benefits or safety are not yet known.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UTSW
RECRUITINGDallas, Texas, 75390, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
Contact
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact