Can a gut bug beat kidney stones?
NCT ID NCT06330246
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving people a live gut bacterium called Oxalobacter formigenes can lower the amount of oxalate in their urine. High urinary oxalate is a major risk factor for calcium oxalate kidney stones. Forty adults with a history of such stones who lack this bacterium will take it by mouth, then follow controlled diets to measure changes in oxalate levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- live Oxalobacter formigenes bacteria
- What this could lead to
- If it works, this could point toward a natural way to reduce kidney stone risk by restoring a helpful gut bacterium.
- What could go wrong
- This is a small, early-stage study with only 40 participants. It tests a short-term effect, and long-term benefits or safety are not yet known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UTSW
RECRUITINGDallas, Texas, 75390, United States
-
University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
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