X-ray-free kidney stone surgery put to the test in 500-patient trial
NCT ID NCT05269108
First seen Jul 30, 2026 · Last updated Aug 14, 2026 · Updated 4 times
Summary
This trial tests whether a common kidney stone procedure called retrograde intrarenal surgery (RIRS) can be performed safely and effectively without using X-ray guidance. Instead, surgeons rely on direct visualization through a tiny camera. The goal is to reduce radiation exposure for both patients and medical staff. The study includes adults with kidney stones at least 10 mm in size and compares stone clearance and complication rates between the standard X-ray-guided approach and the X-ray-free technique.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a surgical procedure for kidney stones performed under direct visualization without X-ray guidance
- What this could lead to
- If successful, this technique could eliminate radiation exposure during kidney stone surgery for both patients and surgeons.
- What could go wrong
- The trial is testing whether skipping X-ray guidance is as safe and effective as the standard approach; there may be a higher risk of complications or incomplete stone removal.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Urology, Al-Azhar University hospitals
Cairo, Egypt
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