A shot of bupivacaine at the surgical site may ease pain after kidney stone surgery — a trial puts it to the test
NCT ID NCT07721571
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This trial tests whether injecting a local anesthetic called bupivacaine into the surgical tract can reduce pain after prone percutaneous nephrolithotomy, a common procedure to remove large kidney stones. Sixty adults scheduled for the surgery will be randomly assigned to receive either standard pain medication alone or standard medication plus a bupivacaine injection along the nephrostomy tract at the end of surgery. Researchers will measure pain levels, time to first painkiller request, total opioid use, and recovery speed to see if this simple addition improves pain control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- bupivacaine injected along the nephrostomy tract at the end of surgery
- What this could lead to
- If effective, this simple, low-cost technique could become a standard way to reduce postoperative pain and opioid use after kidney stone surgery.
- What could go wrong
- This is a small, early-stage trial. The benefit may be modest, and there is a small risk of local anesthetic side effects or injection-related complications.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Urology, Hitit University Çorum Erol Olçok Training and Research Hospital, Çorum, Türkiye
RECRUITINGÇorum, Çorum, 19040, Turkey (Türkiye)
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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