Could your DNA predict thyroid cancer after radiation?

NCT ID NCT04139096

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study investigates whether certain DNA variants make people more likely to develop thyroid cancer after receiving radiation therapy as a child. Researchers will compare the genetic profiles of about 30 people who developed thyroid cancer and 30 who did not, all of whom were treated for a skin hemangioma with radiation decades ago. The goal is to understand how genetics interact with radiation exposure to influence cancer risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could identify genetic markers that predict who is most at risk for radiation-induced thyroid cancer, enabling personalized screening and prevention strategies.
What could go wrong
This is a small, observational study with only 60 participants, so findings may not apply to broader populations. The results may not lead to immediate clinical changes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gustae Roussy

    Villejuif, Val de Marne, 948000, France

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