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Nanocoated screws could make braces work faster

NCT ID NCT07521267

Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of tiny screws used in braces to help move upper front teeth. One type has a special silver-hydroxyapatite coating, while the other is uncoated. Researchers want to see if the coated screws are more successful and allow faster tooth movement. The trial involves 14 teenagers with specific bite problems who need extractions as part of their orthodontic treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
silver-hydroxyapatite nanocoated titanium miniscrews
What this could lead to
If it works, this could lead to more stable and effective orthodontic anchorage, reducing treatment time and complications.
What could go wrong
This is a very small early study with only 14 participants, so results may not apply widely. The coating might not improve success or could cause local irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 14 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Nov 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

14 to 20 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Class I orthodontic cases with bimaxillary protrusion of the anterior segment of the upper jaw that need at least extraction for orthodontic treatment. * Age 14-20 years. * Good oral hygiene with healthy periodontium. * Need for an absolute skeletal anchorage. * Systemically healthy patients. Exclusion Criteria: * Patient with craniofacial anomalies (e.g, cleft lip and palate) * Presence of systemic diseases or syndromes affecting bone metabolism (e.g, osteoporosis, rickets) * Poor oral hygiene or uncooperative patients. * Extensive dental caries or untreated periodontal disease. * History of trauma or surgery affecting the maxilla or mandible.

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Conditions

The condition(s) this trial relates to.

autosomal dominant prognathism Malocclusion, Angle Class I

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Class I malocclusion Maxillary prognathism Orthodontic tooth movement

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dental Medicine (Boys), Al-Azhar University

    RECRUITING

    Cairo, Cairo Governorate, 4434103, Egypt

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