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A shot of your own blood or a laser beam: which can move teeth faster?

NCT ID NCT07795073

Disease control Sponsor: Sana'a University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial compares two methods for speeding up tooth movement in people wearing clear aligners: platelet-rich plasma (PRP) injections and low-level laser therapy (photobiomodulation). Researchers will randomly assign 42 participants to one of three groups: aligners with PRP, aligners with laser therapy, or aligners alone. The study measures how quickly teeth move, how well they track, and any pain reported. The goal is to see if either method can make orthodontic treatment faster and more comfortable.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Platelet-rich plasma (PRP) injection and photobiomodulation (low-level laser therapy), used alongside clear aligners
What this could lead to
If it works, this could shorten orthodontic treatment time and reduce discomfort for people wearing clear aligners.
What could go wrong
This is an early-stage trial with only 42 participants, so results may not apply to everyone. PRP injections and laser therapy carry small risks like pain or swelling at the treatment site.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

About 42 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18- 25 years requiring clear aligner therapy * good oral hygiene and health periodontal status * full permanent dentition (excluding third molars) * willingness to comply with clear aligner wear schedules and follow -up visits. Exclusion Criteria: * history of previous orthodontic treatment * Systemic diseases or conditions affecting bone metabolism * Ongoing pharmacological treatment able to influence orthodontic movement (e.g. prostaglandin inhibitors or biphosphonates) * Active periodontal disease or poor oral hygiene * history of photosensitivity or diseases triggered by light exposure * contraindication to PRP blood extraction

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Orthodontic tooth movement

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry Sanaa university

    Sanaa, Sanaa Governorate, 009671, Yemen

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