Lifestyle overhaul may restore penile blood flow in metabolic syndrome

NCT ID NCT07758842

Recruiting now Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

First seen Aug 11, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This trial tests whether a structured six-month lifestyle modification program can improve penile blood flow and erectile function in men with metabolic syndrome-associated erectile dysfunction. Participants receive dietary counseling, exercise guidance, weight management, smoking cessation support, and sleep and sedentary behavior advice. Erectile function and penile blood flow are measured before and after the program to see if lifestyle changes can help.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: A structured lifestyle modification program including diet, exercise, weight management, smoking cessation, sleep hygiene, and reduced sedentary behavior.
What this could lead to: If successful, this could establish a drug-free, lifestyle-based approach to improving erectile function and blood flow in men with metabolic syndrome.
What could go wrong: This is a small, single-arm study without a control group, so results may be influenced by placebo effects or natural variation. Adherence to lifestyle changes can be challenging, and benefits may not persist long-term.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome erectile dysfunction metabolic syndrome X

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ERECTILE DYSFUNCTION METABOLIC SYNDROME

Contacts and locations

Locations

Al-Hussein University Hospital, Al-Azhar University, Urology Department
RECRUITING

Cairo, 11633, Egypt
Department of Urology, Al-Hussein and Sayed Galal University Hospitals, Al-Azhar University
RECRUITING

Cairo, Egypt

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