Shockwaves may speed up erectile recovery after prostate cancer surgery

NCT ID NCT06717711

Recruiting now Disease control Sponsor: Regina Elena Cancer Institute Source: ClinicalTrials.gov ↗

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This phase 3 trial is testing whether adding low-intensity shockwave therapy to standard erectile dysfunction pills helps men recover erectile function more effectively after robotic prostate cancer surgery. The study involves 158 men who have undergone nerve-sparing surgery and have good erectile function beforehand. Half will receive shockwave therapy plus pills, while the other half will receive pills alone. The goal is to see if the combination leads to better erectile function and quality of life within a year after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Low-intensity extracorporeal shock wave therapy (LiESWT) using a device called PiezoWave2, given alongside PDE5 inhibitor pills
What this could lead to: If effective, this combination could help men recover erectile function faster and more fully after prostate cancer surgery, improving quality of life.
What could go wrong: The trial is still testing the approach, and results may not be conclusive. There is also a risk of minor side effects from the shockwave therapy, though serious complications are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

erectile dysfunction prostate cancer prostate carcinoma Urogenital Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ERECTILE FUNCTION GENITO URINARY CANCER PROSTATE CARCINOMA

Contacts and locations

Locations

IRCCS "Fondazione G. Pascale" National Cancer Institute
RECRUITING

Naples, 80131, Italy
IRCCS "Regina Elena" National Cancer Institute
RECRUITING

Rome, RM, 00144, Italy

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