Can a Plant-Based protein switch reshape your metabolism?

NCT ID NCT04236518

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This trial investigates how replacing animal proteins with plant proteins in the diet influences metabolism. Adults with early signs of metabolic syndrome (like high triglycerides or slightly elevated blood pressure) will follow a controlled diet for four weeks, either predominantly animal or plant protein. At the end, they'll consume a high-fat, high-sugar meal, and blood and urine samples will be analyzed to see how their bodies respond. The goal is to understand the metabolic changes that might come from eating more plant-based proteins.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Controlled diets with predominantly animal or plant protein sources
What this could lead to
If successful, this could help explain how shifting from animal to plant proteins affects metabolism, potentially guiding dietary advice for people at risk of metabolic syndrome.
What could go wrong
This is a small, exploratory study (53 participants) that measures metabolic markers, not long-term health outcomes. Results may not apply to everyone, and the diets are highly controlled, which may not reflect real-world eating habits.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Clermont-Ferrand

    Clermont-Ferrand, 63000, France

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