Fizzing powder may restore skin color in vitiligo

NCT ID NCT05536856

Recruiting now Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new effervescent (fizzing) powder containing 5-fluorouracil to treat vitiligo, a condition that causes white patches on the skin. Sixty people with stable vitiligo will apply either the new fizzing powder or plain 5-fluorouracil powder to their patches. The goal is to see if the fizzing version helps restore skin color better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 5-fluorouracil effervescent powder
What this could lead to: If it works, this could offer a more effective topical treatment for vitiligo repigmentation.
What could go wrong: This is a small, early-stage trial with only 60 people. The improvement may be modest or not last, and 5-fluorouracil can cause skin irritation.

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Conditions

The condition(s) this trial relates to.

vitiligo

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EFFERVESCENT MIXTURE TOPICAL FLUOROURACIL VITILIGO

Contacts and locations

Locations

Facualty of Pharmacy, Al Azhar University
RECRUITING

Cairo, 11765, Egypt

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