New combo drugs aim to ease catheter pain after kidney stone surgery
NCT ID NCT06274333
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding dexmedetomidine or tramadol to standard paracetamol can reduce bladder discomfort caused by urinary catheters after kidney stone surgery. Sixty adults aged 20-50 will receive one of two drug combinations, and their pain and discomfort will be tracked for 24 hours after surgery. The goal is to find a better way to manage this common side effect.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine, tramadol, and paracetamol
What this could lead to
If successful, this could provide a better way to manage catheter-related bladder discomfort after kidney stone surgery, improving patient comfort.
What could go wrong
This is a small, early-stage Phase 3 trial with only 60 participants, so results may not apply to everyone. The drugs also have side effects like sedation or nausea.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Neveen Kohaf
RECRUITINGCairo, Cairo Governorate, 11865, Egypt
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••