New combo drugs aim to ease catheter pain after kidney stone surgery
NCT ID NCT06274333
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding dexmedetomidine or tramadol to standard paracetamol can reduce bladder discomfort caused by urinary catheters after kidney stone surgery. Sixty adults aged 20-50 will receive one of two drug combinations, and their pain and discomfort will be tracked for 24 hours after surgery. The goal is to find a better way to manage this common side effect.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dexmedetomidine, tramadol, and paracetamol
- What this could lead to
- If successful, this could provide a better way to manage catheter-related bladder discomfort after kidney stone surgery, improving patient comfort.
- What could go wrong
- This is a small, early-stage Phase 3 trial with only 60 participants, so results may not apply to everyone. The drugs also have side effects like sedation or nausea.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Neveen Kohaf
RECRUITINGCairo, Cairo Governorate, 11865, Egypt