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A tiny file trick might make root canals less painful

NCT ID NCT07782515

Symptom relief Sponsor: Recep Tayyip Erdogan University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 24, 2026 · Last updated Aug 25, 2026 · Updated 1 time

Summary

This study tests whether a simple technique called apical patency—passing a tiny file slightly beyond the root tip during root canal treatment—can reduce pain afterward. Adults with an infected front tooth will be randomly assigned to receive treatment with or without this extra step, and their pain levels will be tracked for a week. The study also looks at whether the size of the infection seen on a 3D X-ray affects pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Apical patency during root canal treatment (a procedure where a tiny file is passed slightly beyond the root tip)
What this could lead to
If keeping the canal open beyond the root tip reduces pain, it could point to a simple technique to make root canals more comfortable.
What could go wrong
This is a single-center study with a specific tooth type, so results may not apply to all root canals. The procedure carries a small risk of pushing debris beyond the root tip.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

113 people

The number who actually took part.

Started

May 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients. * Systemically healthy and not using regular systemic medications. * A single-rooted maxillary anterior tooth requiring primary root canal treatment. * Diagnosis of chronic apical periodontitis in the study tooth. * The tooth was restorable. * Absence of root fracture or crack. * Absence of internal or external resorption. * Root canal negotiable to the apical region with a small hand file. * Ability to establish a reliable working length. * Availability of a CBCT scan of the relevant maxillary anterior region, previously obtained for clinical purposes or indicated during the treatment process. Exclusion Criteria: * Pregnancy or breastfeeding. * Previous endodontic treatment of the study tooth. * Severe canal calcification. * Suspected root fracture or crack. * Internal or external root resorption. * Periodontal probing depth of 5 mm or greater. * Previous surgical intervention in the relevant region. * Inability to negotiate the root canal. * Inability to establish a reliable working length.

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Conditions

The condition(s) this trial relates to.

chronic apical periodontitis Pain, Postoperative periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Apical periodontitis

Contacts and locations

Locations

  • Recep Tayyip Erdoğan University Faculty of Dentistry, Department of Endodontics

    Rize, Turkey (Türkiye)

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