Mouthwash showdown: can a new formula fight gum disease without staining teeth?
NCT ID NCT07696364
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This study tests whether a chlorhexidine mouthwash with an anti-discoloration system (ADS) can prevent gum inflammation better than a placebo. Healthy volunteers will stop brushing for three weeks and use only the mouthwash to see how well it controls plaque and gingivitis. The goal is to find out if the new formula works as well as standard chlorhexidine without causing tooth staining.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- chlorhexidine mouthwash with or without anti-discoloration system
- What this could lead to
- If effective, this mouthwash could help prevent gum inflammation and plaque buildup without causing tooth staining.
- What could go wrong
- This is a small, early-stage study in healthy volunteers, so results may not apply to everyone. The anti-discoloration system might reduce the mouthwash's effectiveness.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Periodontology, University of Bern
Bern, Canton of Bern, 3010, Switzerland