University Of Bern

This study looks at whether allowing regular cannabis users to buy regulated cannabis from pharmacies helps them switch to safer ways of using it, like vaping or edibles, instead of smoking. About 1,177 participants in Switzerland are randomly assigned to buy from pharmacies or s…

This study looks at how well ceramic (zirconia) dental implants work for replacing a single missing tooth. About 14 people with one missing tooth received a ceramic implant and later a ceramic crown. The main goal is to see how many implants are still working over time.

This study tests whether using four small, one-piece implants with special attachments is better than the standard two-piece implants for holding a lower denture in place. The goal is to improve comfort and quality of life for elderly people who are unhappy with their current den…

This study looks at two ways to replace a missing lower molar with a dental implant. After the tooth is pulled and the bone heals for 12 weeks, some participants get a temporary crown right after implant surgery (immediate loading), while others wait 4 weeks before getting a temp…

This study tests a short, home-based therapy called ASSIP Flex for adults who have attempted suicide. The therapy involves 3-4 sessions delivered in the patient's own environment. Researchers will track suicidal thoughts and behaviors over 12 months to see if the therapy is feasi…

This trial tests whether adding a polygenic risk score (a DNA-based estimate of heart disease risk) to standard risk assessment helps better identify who needs preventive measures like statins or lifestyle changes. About 205 adults aged 40–69 with intermediate cardiovascular risk…

This study aimed to see if chewing xylitol gum could prevent cavities in children aged 5 to 14 living in Ladakh, India. Participants would have chewed gum with either 100% or 22% xylitol daily for a school year. However, the study was withdrawn before any children enrolled, so no…

This study tests whether teaching children in Uganda how to brush their teeth, use fluoride varnish, and eat healthy foods can prevent cavities. About 610 school children aged 5-17 will be split into two groups: one gets the prevention program, the other does not. Researchers wil…

This observational study follows 168 women living with HIV in Zimbabwe who have been treated for cervical pre-cancer. Researchers want to learn how often the disease comes back and whether HPV or DNA tests can predict recurrence. Participants will be monitored every six months fo…

This study follows up with patients who got dental implants along with a sinus lift procedure between 1997 and 2001. Researchers will check bone loss around the implants, take X-rays and photos, and ask patients about their satisfaction. The goal is to see how well these implants…

This study planned to test a fiber-enriched chewing gum (FibreGum) as a way to help with weight management in healthy adults with a BMI between 23 and 40. The goal was to see if people would actually use the gum and find it acceptable, not to measure weight loss directly. However…

This pilot study looks at whether having a family doctor and a pharmacist work together to review medications is practical and helpful for older adults in Switzerland. About 250 people aged 65 and older who take at least five regular medicines and have three or more chronic condi…

This study follows over 2,000 people and their pets in the Canton of Bern to learn how infections like COVID-19 spread and what social and environmental factors influence transmission. Participants provide samples and answer questionnaires over time. The goal is to improve pandem…

This study collects medical information from 3400 people with primary ciliary dyskinesia (PCD) around the world. Researchers will look at symptoms, lung function, growth, and test results to better understand how the disease affects people over time. The goal is to learn more abo…

This study looks at three different timing options for placing a dental implant after losing a tooth in the upper front jaw: same day, after 1-4 months, or after more than 4 months. Researchers want to see which approach gives the best results for the cost. About 160 adults who n…