Can a camera inside the womb replace the need for a biopsy?

NCT ID NCT07707570

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
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The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study looks at women who have bleeding after menopause. Doctors will use a tiny camera (hysteroscopy) to look inside the womb and compare what they see with the results of a tissue sample (biopsy). The goal is to see how well the camera exam can detect problems like polyps, thickening, or cancer. The findings could help make diagnosis faster and less invasive.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better diagnose the cause of postmenopausal bleeding without needing more invasive tests.
What could go wrong
This is a small, observational study at a single hospital, so results may not apply to all women. It does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet). I. Clinical Assessment * Detailed history including: * Duration since menopause * Pattern and duration of bleeding * Obstetric and medical history * General abdominal and pelvic examination II. Transvaginal Ultrasound (TVS) * Measurement of endometrial thickness * Assessment of uterine and adnexal pathology III. Hysteroscopic Examination Hysteroscopy will be performed using a rigid hysteroscope to evaluate: * Endometrial appearance * Presence of polyps, hyperplasia, or malignancy Hysteroscopic findings will be classified as: * Normal (proliferative, secretory, atrophic) * Abnormal (polyp, hyperplasia, carcinoma, fibroid) (1,3) Criteria suggestive of: * Hyperplasia: irregular thickened endometrium, increased vascularity (1,3) * Carcinoma: irregular necrotic tissue, atypical vessels, friable surface (1,3) IV. Endometrial Sampling • Directed biopsy will be taken from su

Ages

45 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria : * Postmenopausal women presenting with uterine bleeding * Age ≥ 45 years \*Exclusion criteria: * Women on hormone replacement therapy * Bleeding due to vulvar, vaginal, cervical, or urethral causes * Patients on anticoagulant therapy * Patients unfit for hysteroscopy * Refusal to participate

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As listed by the trial registrant

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How to take part

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