Can a camera inside the womb replace the need for a biopsy?
NCT ID NCT07707570
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This study looks at women who have bleeding after menopause. Doctors will use a tiny camera (hysteroscopy) to look inside the womb and compare what they see with the results of a tissue sample (biopsy). The goal is to see how well the camera exam can detect problems like polyps, thickening, or cancer. The findings could help make diagnosis faster and less invasive.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better diagnose the cause of postmenopausal bleeding without needing more invasive tests.
- What could go wrong
- This is a small, observational study at a single hospital, so results may not apply to all women. It does not test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet). I. Clinical Assessment * Detailed history including: * Duration since menopause * Pattern and duration of bleeding * Obstetric and medical history * General abdominal and pelvic examination II. Transvaginal Ultrasound (TVS) * Measurement of endometrial thickness * Assessment of uterine and adnexal pathology III. Hysteroscopic Examination Hysteroscopy will be performed using a rigid hysteroscope to evaluate: * Endometrial appearance * Presence of polyps, hyperplasia, or malignancy Hysteroscopic findings will be classified as: * Normal (proliferative, secretory, atrophic) * Abnormal (polyp, hyperplasia, carcinoma, fibroid) (1,3) Criteria suggestive of: * Hyperplasia: irregular thickened endometrium, increased vascularity (1,3) * Carcinoma: irregular necrotic tissue, atypical vessels, friable surface (1,3) IV. Endometrial Sampling • Directed biopsy will be taken from su
- Ages
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45 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria : * Postmenopausal women presenting with uterine bleeding * Age ≥ 45 years \*Exclusion criteria: * Women on hormone replacement therapy * Bleeding due to vulvar, vaginal, cervical, or urethral causes * Patients on anticoagulant therapy * Patients unfit for hysteroscopy * Refusal to participate
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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