Less invasive surgery may improve recovery for ovarian cancer patients
NCT ID NCT04575935
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two surgical approaches for people with advanced ovarian, fallopian tube, or primary peritoneal cancer who have received chemotherapy before surgery. One group will have minimally invasive surgery (small incisions), and the other will have standard open surgery (larger incision). The goal is to see if the less invasive method works as well or better at delaying cancer return and improving quality of life. About 580 participants will be enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Minimally invasive surgery (laparoscopy)
What this could lead to
If successful, this could show that a less invasive surgery works as well as open surgery, helping patients recover faster with less pain and a better quality of life after treatment.
What could go wrong
This is a large Phase 3 trial, but it is still possible that minimally invasive surgery may not control the cancer as effectively as open surgery, or that benefits are small. Results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Amsterdam UMC - Locatie AMC | H5Zuid 154
RECRUITINGAmsterdam, Netherlands
Contact
Contact
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Arthur J.E. Child Comprehensive Cancer Centre - Calgary
RECRUITINGCalgary, Canada
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Contact Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Contact Email: •••••@•••••
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Cleveland Clinic Foundation - Florida
RECRUITINGWeston, Florida, 33331, United States
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Contact Email: •••••@•••••
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
Contact Email: •••••@•••••
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Duke
RECRUITINGDurham, North Carolina, 27710, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITINGRome, 00168, Italy
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Contact Email: •••••@•••••
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Houston Methodist
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Email: •••••@•••••
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Instituto Nacional de Cancerología (Mexico)
RECRUITINGTlalpan, Mexico
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Contact Email: •••••@•••••
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Lyndon Baines Johnson General
RECRUITINGHouston, Texas, 77026, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
Contact Email: •••••@•••••
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NYU Langone Health
RECRUITINGMineola, New York, 11501, United States
Contact Email: •••••@•••••
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Sant'Orsola Hospital di Bologna
RECRUITINGBologna, 40138, Italy
Contact
Contact Email: •••••@•••••
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St. Luke's University Health Network
RECRUITINGBethlehem, Pennsylvania, 18015, United States
Contact Email: •••••@•••••
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University Health Network - Princess Margaret Cancer Centre
RECRUITINGToronto, Canada
Contact
Contact Email: •••••@•••••
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University of Miami Miller School of Medicine-Sylvester Cancer Center
RECRUITINGMiami, Florida, 33136, United States
Contact Email: •••••@•••••
Contact
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University of Wisconsin Carbone Cancer Center
ACTIVE_NOT_RECRUITINGMadison, Wisconsin, 53792, United States