ADVANCED BREAST CARCINOMA
Clinical trials for ADVANCED BREAST CARCINOMA explained in plain language.
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New drug shows promise for Hard-to-Treat breast cancer subtype
Disease control Recruiting nowThis study tests a drug called trastuzumab deruxtecan (T-DXd) against the usual treatment (a CDK4/6 inhibitor plus hormone therapy) for people with a certain type of advanced breast cancer. The cancer must be hormone receptor-positive, HER2-low or ultralow, and have a specific ge…
Matched conditions: ADVANCED BREAST CARCINOMA
Phase: PHASE2 • Sponsor: MedSIR • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Can new drug combos outsmart PARP resistance in BRCA breast cancer?
Disease control Recruiting nowThis phase 2 trial tests whether adding cediranib or ceralasertib to olaparib can overcome resistance in BRCA-mutated advanced breast cancer. About 60 participants with HER2-negative, BRCA-positive tumors that have progressed on prior therapy will receive one of the two drug comb…
Matched conditions: ADVANCED BREAST CARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Electric field device combined with drugs tested for advanced cancers
Disease control Recruiting nowThis early-phase trial tests a wearable device that creates electric fields (tumor treating fields) combined with either cabozantinib or nab-paclitaxel and atezolizumab in 43 people with advanced solid tumors in the abdomen or chest. The goal is to find the safest dose and see if…
Matched conditions: ADVANCED BREAST CARCINOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Cancer care at home: a game changer for patients?
Symptom relief Recruiting nowThis study compares giving cancer treatment at home versus in the clinic for people with advanced cancers. The goal is to see if home treatment reduces stress, financial burden, and improves overall experience. About 220 participants will be randomly assigned to receive their reg…
Matched conditions: ADVANCED BREAST CARCINOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 12:10 UTC
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What do people with advanced breast cancer really need? new study aims to find out
Knowledge-focused Recruiting nowThis study looks at what helps and what is hard for people with advanced breast cancer, and what kind of support they still need. Researchers will talk to 50 patients and review their medical records to understand their experiences. The goal is to learn how to improve care and su…
Matched conditions: ADVANCED BREAST CARCINOMA
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC