Could a parasite drug boost cancer immunotherapy? new trial investigates
NCT ID NCT05318469
First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times
Summary
This study tests whether adding ivermectin (a drug used for parasitic infections) to standard immunotherapy drugs (balstilimab or pembrolizumab) can shrink tumors in people with metastatic triple-negative breast cancer. The trial has two phases: first, finding the safest dose of ivermectin, and second, checking how well the combination works. About 34 participants will be enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ivermectin combined with balstilimab or pembrolizumab
- What this could lead to
- If it works, this could offer a new treatment option for people with metastatic triple-negative breast cancer, potentially shrinking tumors and extending life.
- What could go wrong
- This is an early-phase trial with only 34 participants, so results are uncertain. Ivermectin is not a standard cancer drug, and combining it with immunotherapy may cause unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cedars-Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
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