Could a parasite drug boost cancer immunotherapy? new trial investigates

NCT ID NCT05318469

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding ivermectin (a drug used for parasitic infections) to standard immunotherapy drugs (balstilimab or pembrolizumab) can shrink tumors in people with metastatic triple-negative breast cancer. The trial has two phases: first, finding the safest dose of ivermectin, and second, checking how well the combination works. About 34 participants will be enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ivermectin combined with balstilimab or pembrolizumab

What this could lead to

If it works, this could offer a new treatment option for people with metastatic triple-negative breast cancer, potentially shrinking tumors and extending life.

What could go wrong

This is an early-phase trial with only 34 participants, so results are uncertain. Ivermectin is not a standard cancer drug, and combining it with immunotherapy may cause unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact