New injection plus chemo-radiation targets tough head and neck tumors

NCT ID NCT07219212

Recruiting now Disease control Sponsor: Johnson & Johnson Enterprise Innovation Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This early-stage study is testing whether a new drug, JNJ-90301900, is safe and works when injected directly into tumors along with standard chemotherapy and radiation. It involves 30 adults with advanced head and neck cancer. The main goal is to check for side effects and see how well the combination shrinks tumors.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SQUAMOUS CELL CARCINOMA OF HEAD AND NECK

Contacts and locations

Locations

Aichi Cancer Center
RECRUITING

Nagoya, 464-8681, Japan
Boston Medical Center
RECRUITING

Boston, Massachusetts, 02118, United States
Centre Henri Becquerel
RECRUITING

Rouen, 76038, France
Centre Oscar Lambret
RECRUITING

Lille, 59000, France
City of Hope
RECRUITING

Duarte, California, 91010, United States
Emory University
RECRUITING

Atlanta, Georgia, 30308, United States
Gustave Roussy
RECRUITING

Villejuif, 94805, France
Hiroshima University Hospital
RECRUITING

Hiroshima, 734 8551, Japan
Hopital De La Cavale Blanche
RECRUITING

Brest, 29200, France
Hopital La Timone
RECRUITING

Marseille, 13385, France
Mayo Clinic
RECRUITING

Jacksonville, Florida, 32224, United States
Moffit Cancer center
RECRUITING

Tampa, Florida, 33612, United States
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10467, United States
Shizuoka Cancer Center
RECRUITING

Shizuoka, 411 8777, Japan
Tokyo Medical University Hospital
RECRUITING

Tokyo, 160-0023, Japan
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294, United States
University of California at San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States
University of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27514, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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