New study aims to decode head and neck tumors using MRI and tissue tests

NCT ID NCT06085781

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at how head and neck tumors change during treatment using special MRI scans and tissue samples. Sixty adults with newly diagnosed head and neck cancer will take a pill called pimonidazole, which highlights low-oxygen areas in tumors, and undergo repeat imaging. The goal is to find markers that could guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pimonidazole (oral tablet) and functional MRI

What this could lead to

If successful, this could help doctors predict how head and neck tumors respond to treatment, leading to more personalized therapy plans.

What could go wrong

This is an early exploratory study with only 60 participants, so results may not apply to all patients. The biomarkers studied may not prove useful in practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SQUAMOUS CELL CARCINOMA OF HEAD AND NECK are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Princess Margaret Cancer Center

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••