Could a yeast vaccine stop Cancer's return?

NCT ID NCT05952934

Recruiting now Disease control Sponsor: University of Arkansas Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a vaccine made from candida (a type of yeast) to see if it can reduce the risk of head and neck cancer coming back. About 100 adults who have finished cancer treatment and are currently cancer-free will receive either the vaccine or a placebo over two years. The goal is to compare recurrence rates between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Candin (candida therapeutic vaccine)
What this could lead to: If it works, this could offer a new way to lower the chance of head and neck cancer coming back after standard treatment.
What could go wrong: This is an early phase II trial with only 100 people, so results may not apply to everyone. The vaccine may not reduce recurrence and could cause side effects like injection site reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SQUAMOUS CELL CARCINOMA OF HEAD AND NECK

Contacts and locations

Locations

Highlands Oncology Group, PA
RECRUITING

Fayetteville, Arkansas, 72762, United States
Highlands Oncology Group, PA
RECRUITING

Rogers, Arkansas, 75758, United States
Highlands Oncology Group, PA
RECRUITING

Springdale, Arkansas, 72762, United States
Perlmutter Cancer Center at NYU Langone Health
RECRUITING

Mineola, New York, 11501, United States
Perlmutter Cancer Center at NYU Langone Health
RECRUITING

New York, New York, 10016, United States
University of Arkansas for Medical Sciences
RECRUITING

Little Rock, Arkansas, 72205, United States

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