New drug cocktail aims to wipe out aggressive breast cancer before surgery

NCT ID NCT06966700

Recruiting now Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 10 times

Summary

This phase 3 trial is testing whether adding a targeted therapy called Sacituzumab tirumotecan (Sac-TMT) to standard chemotherapy and immunotherapy (pembrolizumab) can better eliminate cancer before surgery in people with high-risk, early-stage triple-negative or hormone-receptor-low/HER2-negative breast cancer. About 2,400 participants will be randomly assigned to receive either the new combination or standard chemo plus pembrolizumab. The main goals are to see if more patients have no cancer left at surgery and if they live longer without the cancer returning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sacituzumab tirumotecan (Sac-TMT) plus pembrolizumab and chemotherapy
What this could lead to: If successful, this could offer a more effective pre-surgery treatment for aggressive breast cancers, potentially increasing the chance of eliminating all cancer before surgery and delaying recurrence.
What could go wrong: This is a large phase 3 trial, but the added drug (Sac-TMT) may cause more side effects and it is not yet proven to improve long-term survival. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autosomal dominant Parkinson disease 4 breast neoplasm hormone receptor-positive breast cancer triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST NEOPLASMS HR LOW-POSITIVE/HER2-NEGATIVE BREAST NEOPLASMS TRIPLE NEGATIVE BREAST NEOPLASMS

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

ASST Papa Giovanni XXIII ( Site 4511)
RECRUITING

Bergamo, 24127, Italy
ATHENS MEDICAL CENTER ( Site 4100)
RECRUITING

Marousi, Attica, 151 25, Greece
AZORG Campus Aalst-Moorselbaan ( Site 3201)
RECRUITING

Aalst, Oost-Vlaanderen, 9300, Belgium
AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0044)
RECRUITING

Altamonte Springs, Florida, 32701, United States
Akademiska sjukhuset ( Site 3801)
RECRUITING

Uppsala, Uppsala County, 751 85, Sweden
Akershus Universitetssykehus ( Site 3701)
RECRUITING

Lørenskog, Akershus, 1474, Norway
Akita University Hospital ( Site 2302)
RECRUITING

Akita, 010-8543, Japan
Altru Health System ( Site 0057)
RECRUITING

Grand Forks, North Dakota, 58201, United States
Anhui Provincial Cancer Hospital ( Site 2234)
RECRUITING

Hefei, Anhui, 230031, China
Ankara Bilkent Şehir Hastanesi. ( Site 5114)
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Arcispedale Santa Maria Nuova ( Site 4510)
RECRUITING

Reggio Emilia, 42123, Italy
Aretaieio Hospital Oncology Unit ( Site 4101)
RECRUITING

Athens, Attica, 115 28, Greece
Asan Medical Center ( Site 1803)
RECRUITING

Seoul, 05505, South Korea
Asociacion Española de Beneficencia ( Site 6403)
ACTIVE_NOT_RECRUITING

Guatemala City, 01015, Guatemala
Associação Hospitalar Beneficente São Vicente de Paulo ( Site 6115)
RECRUITING

Passo Fundo, Rio Grande do Sul, 99010-080, Brazil
Auckland City Hospital ( Site 1000)
RECRUITING

Auckland, 1023, New Zealand
Avera Cancer Institute - Yankton ( Site 0089)
RECRUITING

Yankton, South Dakota, 57078, United States
Avera McKennan Hospital ( Site 0002)
RECRUITING

Sioux Falls, South Dakota, 57105, United States
Azienda Ospedaliero Universitaria Pisana ( Site 4506)
RECRUITING

Pisa, 56126, Italy
Azienda Ospedaliero Universitaria delle Marche ( Site 4509)
RECRUITING

Ancona, 60126, Italy
Azienda USL Toscana Nord Ovest_Ospedale Civile di Livorno ( Site 4503)
RECRUITING

Livorno, Tuscany, 57124, Italy
BC Cancer - Surrey ( Site 0217)
RECRUITING

Surrey, British Columbia, V3V 1Z2, Canada
BC Cancer Vancouver ( Site 0218)
RECRUITING

Vancouver, British Columbia, V5Z 4E6, Canada
Bacs-Kiskun Varmegyei Oktatokorhaz-Onkoradiologiai Kozpont ( Site 4207)
RECRUITING

Kecskemét, Bács-Kiskun county, 6000, Hungary
Banner MD Anderson Cancer Center ( Site 0066)
RECRUITING

Gilbert, Arizona, 85234, United States
Basken Adana Dr.Turgut Noyan Uygulama ve Arastirma Merkezi. ( Site 5112)
RECRUITING

Adana, 01250, Turkey (Türkiye)
Beijing Cancer Hospital ( Site 2201)
RECRUITING

Beijing, Beijing Municipality, 100142, China
Bialostockie Centrum Onkologii im.M.Sklodowskiej-Curie ( Site 4608)
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-027, Poland
Bioresearch Partner ( Site 0072)
RECRUITING

Hialeah, Florida, 33013, United States
Blackpool Victoria Hospital ( Site 5310)
RECRUITING

Blackpool, FY3 8NR, United Kingdom
Bon Secours Cancer Institute at St. Francis ( Site 0048)
RECRUITING

Midlothian, Virginia, 23114, United States
Borsod-Abaúj-Zemplén Vármegyei Központi Kórház És Egyetemi Oktatókórház ( Site 4208)
RECRUITING

Miskolc, Borsod-Abauj Zemplen county, 3526, Hungary
Bowen Icon Cancer Centre ( Site 1001)
RECRUITING

Crofton Downs, Wellington Region, 6035, New Zealand
Bradfordhill ( Site 6202)
RECRUITING

Santiago, Region M. de Santiago, 8420383, Chile
CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 4907)
RECRUITING

Port Elizabeth, Eastern Cape, 6045, South Africa
CELAN,S.A ( Site 6401)
RECRUITING

Guatemala City, 01010, Guatemala
CHU UCL Namur/Site Sainte Elisabeth ( Site 3203)
RECRUITING

Namur, 5000, Belgium
CHU d'Amiens-Picardie - Hôpital Sud ( Site 3908)
RECRUITING

Amiens, Somme, 80054, France
CHU de Quebec Universite Laval - Hopital du Saint-Sacrement ( Site 0203)
RECRUITING

Québec, Quebec, G1S 4L8, Canada
CHUS - Hospital Clinico Universitario ( Site 5006)
RECRUITING

Santiago de Compostela, La Coruna, 19706, Spain
CNCE Precarpathian Clinical Oncologic Center ( Site 5201)
RECRUITING

Ivano-Frankivsk, Ivano-Frankivsk Oblast, 76018, Ukraine
CNE Regional clinical oncology center of Kirovograd regional Council ( Site 5203)
RECRUITING

Kropyvnytsky, Kirovohrad Oblast, 25011, Ukraine
COMMUNAL NONPROFIT ENTERPRISE CLINICAL CENTER OF ONCOLOGY, HEMATOLOGY, TRANSPLANTOLOGY AND PALLIATI ( Site 5207)
RECRUITING

Cherkasy, Cherkasy Oblast, 18009, Ukraine
Cabinet Medical Oncomed ( Site 4803)
RECRUITING

Timișoara, Timiș County, 300239, Romania
Cancer Care Northwest ( Site 0003)
RECRUITING

Spokane, Washington, 99202, United States
Cancer Partners of Nebraska ( Site 0068)
RECRUITING

Lincoln, Nebraska, 68516, United States
Cancercare Rondebosch Oncology ( Site 4906)
RECRUITING

Cape Town, Western Cape, 7700, South Africa
CaritasKlinikum Saarbruecken St. Theresia ( Site 4014)
RECRUITING

Saarbrücken, Saarland, 66113, Germany
Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer-Medical Oncology ( Site 3900)
RECRUITING

Rennes, Ille-et-Vilaine, 35000, France
Centre Georges Francois Leclerc ( Site 3902)
RECRUITING

Dijon, Bourgogne-Franche-Comté, 21000, France
Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman ( Site 3204)
RECRUITING

Liège, Liege, 4000, Belgium
Centre Hospitalier de l'Université de Montréal ( Site 0201)
RECRUITING

Montreal, Quebec, H2X 3E4, Canada
Centre de Cancerologie du Grand Montpellier ( Site 3910)
RECRUITING

Montpellier, Herault, 34070, France
Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec ( Site 0204)
RECRUITING

Trois-Rivières, Quebec, G8Z 3R9, Canada
Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer ( Site 0206)
RECRUITING

Sherbrooke, Quebec, J1H 5N4, Canada
Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC) ( Site 6005)
RECRUITING

Buenos Aires, Buenos Aires F.D., C1431FWO, Argentina
Centro de Estudios Clínicos SAGA ( Site 6205)
RECRUITING

Santiago, Region M. de Santiago, 7500653, Chile
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 4616)
RECRUITING

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-796, Poland
Chang Gung Medical Foundation-Linkou Branch ( Site 1906)
RECRUITING

Taoyuan, 33305, Taiwan
Chiba Cancer Center ( Site 2303)
RECRUITING

Chiba, 260-8717, Japan
Chris O'Brien Lifehouse ( Site 1206)
RECRUITING

Camperdown, New South Wales, 2050, Australia
Chulalongkorn University ( Site 2001)
RECRUITING

Pathumwan, Bangkok, 10330, Thailand
City of Hope Cancer Center - Atlanta ( Site 0102)
RECRUITING

Newnan, Georgia, 30265, United States
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 6309)
RECRUITING

Bogotá, Bogota D.C., 111321, Colombia
Clínica Mayo de Urgencias Médicas Cruz Blanca S.R.L ( Site 6006)
RECRUITING

San Miguel de Tucumán, Tucumán Province, T4000IHE, Argentina
Clínica de Oncologia Reichow ( Site 6112)
RECRUITING

Blumenau, Santa Catarina, 89010-340, Brazil
Colchester General Hospital ( Site 5307)
RECRUITING

Colchester, Essex, CO4 5JL, United Kingdom
Community Cancer Institute ( Site 0100)
RECRUITING

Clovis, California, 93611, United States
Complejo asistencial universitario de Salamanca ( Site 5000)
RECRUITING

Salamanca, Castille and León, 37007, Spain
Deyang City People's Hospital ( Site 2244)
RECRUITING

Deyang, Sichuan, 618099, China
Drammen Sykehus, Vestre Viken HF ( Site 3700)
RECRUITING

Drammen, Buskerud, 3004, Norway
El Camino Hospital Cancer Center ( Site 0096)
RECRUITING

Mountain View, California, 94040, United States
Erciyes University ( Site 5119)
RECRUITING

Kayseri, 38039, Turkey (Türkiye)
European Interbalkan Medical Center ( Site 4103)
RECRUITING

Thessaloniki, 570 01, Greece
FALP ( Site 6200)
RECRUITING

Santiago, Region M. de Santiago, 7500921, Chile
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 6311)
RECRUITING

Bogotá, Bogota D.C., 110131, Colombia
Faculty of Medicine Siriraj Hospital ( Site 2000)
RECRUITING

Bangkok, Bangkok, 10700, Thailand
Fakultni nemocnice Hradec Kralove-Klinika onkologie a radioterapie ( Site 3403)
RECRUITING

Hradec Králové, 500 05, Czechia
Florida Cancer Specialists - North ( Site 7002)
RECRUITING

St. Petersburg, Florida, 33701, United States
Florida Cancer Specialists - South ( Site 7004)
RECRUITING

Fort Myers, Florida, 33901, United States
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 4501)
RECRUITING

Milan, 20133, Italy
Fondazione IRCCS San Gerardo dei Tintori ( Site 4513)
RECRUITING

Monza, Lombardy, 20900, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 4500)
RECRUITING

Roma, 00168, Italy
Fort Wayne Medical Oncology and Hematology ( Site 0084)
RECRUITING

Fort Wayne, Indiana, 46804, United States
Franciscan Health ( Site 0077)
RECRUITING

Indianapolis, Indiana, 46237, United States
Fred Hutchinson Cancer Center ( Site 0069)
RECRUITING

Seattle, Washington, 98109, United States
Fudan University Shanghai Cancer Center ( Site 2209)
RECRUITING

Shanghai, Shanghai Municipality, 200000, China
Fukushima Medical University Hospital ( Site 2301)
RECRUITING

Fukushima, 960-1295, Japan
Fundacion Ars Medica ( Site 6004)
RECRUITING

San Salvador de Jujuy, Jujuy Province, Y4600EHA, Argentina
Fundación Valle del Lili ( Site 6308)
RECRUITING

Cali, Valle del Cauca Department, 760032, Colombia
Fundação Pio XII - Hospital de Câncer de Barretos ( Site 6108)
RECRUITING

Barretos, São Paulo, 14784-400, Brazil
General Hospital of Athens - Laiko ( Site 4104)
RECRUITING

Athens, Attica, 115 27, Greece
Good Samaritan Hospital-TriHealth Cancer institute ( Site 0027)
RECRUITING

Cincinnati, Ohio, 45220, United States
Guangdong Maternity and Child Health Care Hospital ( Site 2251)
RECRUITING

Guangzhou, Guangdong, 511400, China
Guangxi Medical University Affiliated Tumor Hospital ( Site 2223)
RECRUITING

Nanning, Guangxi, 530201, China
HENRI MONDOR HOSPITAL ( Site 3904)
RECRUITING

Créteil, Val-de-Marne, 94010, France
HOSPITAL UNIVERSITARIO DE JAEN ( Site 5003)
RECRUITING

Jaén, Jaen, 23007, Spain
HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 5004)
RECRUITING

Pozuelo de Alarcón, Madrid, 28223, Spain
Hacettepe Universitesi Tip Fakultesi Hastanesi ( Site 5110)
RECRUITING

Sıhhiye, Ankara, 06230, Turkey (Türkiye)
Hackensack Univ Medical Center (HUMC) ( Site 0007)
RECRUITING

Hackensack, New Jersey, 07601, United States
Hanoi Oncology Hospital ( Site 2101)
RECRUITING

Hanoi, Hanoi, 100000, Vietnam
Harbin Medical University Cancer Hospital ( Site 2204)
RECRUITING

Haerbin, Heilongjiang, 150081, China
Health Sciences North ( Site 0234)
RECRUITING

Greater Sudbury, Ontario, P3E 5J1, Canada
Helios Clinical Research ( Site 0061)
RECRUITING

Whittier, California, 90602, United States
Helios Klinikum Berlin-Buch ( Site 4008)
RECRUITING

Berlin, 13125, Germany
Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus) ( Site 3600)
RECRUITING

Helsinki, Uusimaa, 00029, Finland
Henan Cancer Hospital ( Site 2238)
RECRUITING

Zhengzhou, Henan, 450000, China
Hendrick Medical Center ( Site 0009)
RECRUITING

Abilene, Texas, 79601, United States
Hiroshima City Hiroshima Citizens Hospital ( Site 2318)
RECRUITING

Hiroshima, 730-8518, Japan
Hoag Memorial Hospital Presbyterian ( Site 0010)
RECRUITING

Newport Beach, California, 92663, United States
Hong Kong United Oncology Centre ( Site 1304)
RECRUITING

Jordan, Hong Kong
Hospital Araújo Jorge ( Site 6100)
RECRUITING

Goiânia, Goiás, 74605-070, Brazil
Hospital Beata María Ana ( Site 5010)
RECRUITING

Madrid, +34914097423, Spain
Hospital General de Valencia ( Site 5008)
RECRUITING

Valencia, Valenciana, Comunitat, 46014, Spain
Hospital Guillermo Almenara Irigoyen ( Site 6601)
RECRUITING

Lima, 15001, Peru
Hospital Italiano de Buenos Aires-ginecology ( Site 6003)
RECRUITING

Buenos Aires, Buenos Aires F.D., C1199ABB, Argentina
Hospital Nacional Edgardo Rebagliati Martins ( Site 6602)
RECRUITING

Lima, 15072, Peru
Hospital Pulau Pinang ( Site 1502)
RECRUITING

George Town, Pulau Pinang, 10450, Malaysia
Hospital São Lucas da PUCRS ( Site 6103)
RECRUITING

Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
Hospital Universitario Virgen Macarena ( Site 5002)
RECRUITING

Seville, 41009, Spain
Hospital de Base de São José do Rio Preto ( Site 6101)
RECRUITING

São José do Rio Preto, São Paulo, 15090-000, Brazil
Hospital de Basurto ( Site 5007)
RECRUITING

Bilbao, Bizkaia, 48013, Spain
Hospital de Cascais Doutor José de Almeida ( Site 4700)
RECRUITING

Lisbon, 2755-009, Portugal
Huddersfield Royal Infirmary ( Site 5313)
RECRUITING

Huddersfield, England, HD3 3EA, United Kingdom
Hunan Cancer Hospital ( Site 2232)
RECRUITING

Changsha, Hunan, 410006, China
I.U. Cerrahpasa Medical Faculty ( Site 5111)
RECRUITING

Istanbul, 34098, Turkey (Türkiye)
IMAT S.A.S ( Site 6300)
RECRUITING

Montería, Departamento de Córdoba, 230002, Colombia
INCA Hospital do Câncer III ( Site 6107)
RECRUITING

Rio de Janeiro, 20560-120, Brazil
INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS ( Site 6604)
RECRUITING

Surquillo, Muni Metro de Lima, 15038, Peru
INTEGRA Cancer Institute ( Site 6404)
RECRUITING

Guatemala City, 01010, Guatemala
IPOR Instituto Peruano de Oncología & Radioterapia ( Site 6600)
RECRUITING

Lima, 15036, Peru
IRCCS Azienda Ospedaliera Metropolitana ( Site 4508)
RECRUITING

Genova, 16132, Italy
InVO Institut für Versorgungsforschung in der Onkologie ( Site 4009)
RECRUITING

Koblenz, Rhineland-Palatinate, 56068, Germany
Institut Català d'Oncologia - L'Hospitalet ( Site 5001)
RECRUITING

L'Hospitalet de Llobregat, Barcelona, 08908, Spain
Institut Curie ( Site 3903)
RECRUITING

Paris, 75248, France
Institut Curie - site Saint-Cloud ( Site 3909)
RECRUITING

Saint-Cloud, Hauts-de-Seine, 92210, France
Institut Paoli Calmettes. ( Site 3906)
RECRUITING

Marseille, Bouches-du-Rhone, 13009, France
Instituto Portugues de Oncologia do Porto ( Site 4705)
RECRUITING

Porto, 4200-072, Portugal
Instituto Regional de Enfermedades Neoplasicas del Centro (IREN CENTRO) ( Site 6605)
RECRUITING

Concepción, Departamento de Junín, 12125, Peru
Instituto Regional de Enfermedades Neoplásicas Del Norte ( Site 6606)
RECRUITING

Trujillo, La Libertad, 13001, Peru
Instituto de Investigaciones Clinicas Mar del Plata ( Site 6008)
RECRUITING

Mar del Plata, Buenos Aires, B7600FZO, Argentina
Institutul Oncologic Cluj ( Site 4802)
RECRUITING

Cluj-Napoca, 400015, Romania
Institutul Regional de Oncologie ( Site 4805)
RECRUITING

Iași, 700483, Romania
Intermountain Health Cancer Center Saint Joseph ( Site 0062)
RECRUITING

Denver, Colorado, 80218, United States
Intermountain Health St. Mary's Regional Hospital ( Site 0054)
RECRUITING

Grand Junction, Colorado, 81501, United States
Intermountain Medical Center ( Site 0074)
RECRUITING

Murray, Utah, 84107, United States
Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 6102)
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035-074, Brazil
Istituto Nazionale Tumori Regina Elena ( Site 4512)
RECRUITING

Roma, 00144, Italy
JPS Oncology and Infusion Center ( Site 0083)
RECRUITING

Fort Worth, Texas, 76104, United States
Jessa Ziekenhuis ( Site 3200)
RECRUITING

Hasselt, Limburg, 3500, Belgium
Jiangmen Central Hospital ( Site 2243)
RECRUITING

Jiangmen, Guangdong, 529030, China
Jiangsu Province Hospital ( Site 2216)
RECRUITING

Nanjing, Jiangsu, 210003, China
Jinan Central Hospital ( Site 2249)
RECRUITING

Jinan, Shandong, 250013, China
Kanagawa Cancer Center ( Site 2308)
RECRUITING

Yokohama, Kanagawa, 241-8515, Japan
Kanazawa Medical University Hospital ( Site 2321)
RECRUITING

Kahoku-gun, Ishikawa-ken, 920-0293, Japan
Kansai Medical University Hospital ( Site 2317)
RECRUITING

Hirakata, Osaka, 573-1191, Japan
Karolinska Universitetssjukhuset Solna ( Site 3800)
RECRUITING

Stockholm, Stockholm County, 171 64, Sweden
Kelsey-Seybold Clinic ( Site 0042)
RECRUITING

Houston, Texas, 77025, United States
Kelsey-Seybold Clinic ( Site 0088)
RECRUITING

Houston, Texas, 77025, United States
Kindai University Hospital ( Site 2316)
RECRUITING

Sakai, Osaka, 590-0197, Japan
Klinikum der Ludwig-Maximilians-Universitaet Muenchen ( Site 4015)
RECRUITING

Munich, Bavaria, 80336, Germany
Krajska nemocnice Liberec a.s.-Komplexni onkologicke centrum ( Site 3404)
RECRUITING

Liberec, 460 01, Czechia
Kumamoto Shinto General Hospital ( Site 2322)
RECRUITING

Kumamoto, 862-8655, Japan
Kyoto University Hospital ( Site 2313)
RECRUITING

Kyoto, 606-8507, Japan
Kyungpook National University Chilgok Hospital ( Site 1805)
RECRUITING

Taegu, Taegu-Kwangyokshi, 41404, South Korea
LIFE GROENKLOOF-Mary Potter Cancer Centre ( Site 4901)
RECRUITING

Pretoria, Gauteng, 0181, South Africa
Lakeridge Health ( Site 0225)
RECRUITING

Oshawa, Ontario, L1G 2B9, Canada
Leicester Royal Infirmary ( Site 5309)
RECRUITING

Leicester, LE1 5WW, United Kingdom
Liga Norte Riograndense Contra o Câncer ( Site 6111)
RECRUITING

Natal, Rio Grande do Norte, 59062-000, Brazil
LinYi Cancer Hospital ( Site 2248)
RECRUITING

Linyi, Shandong, 276034, China
Liuzhou People's Hospital ( Site 2259)
RECRUITING

Liuzhou, Guangxi, 545006, China
Louisiana State University Health Sciences Shreveport ( Site 0053)
RECRUITING

Shreveport, Louisiana, 71103, United States
MEDI-K ( Site 6400)
RECRUITING

Guatemala City, 01009, Guatemala
MacKay Memorial Hospital ( Site 1903)
RECRUITING

Taipei, 10449, Taiwan
Macquarie University ( Site 1203)
RECRUITING

North Ryde, New South Wales, 2109, Australia
Maharaj Nakorn Chiang Mai Hospital ( Site 2003)
RECRUITING

Muang, Chiang Mai, 50200, Thailand
Makati Medical Center ( Site 1609)
RECRUITING

Makati City, National Capital Region, 1229, Philippines
Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 3400)
RECRUITING

Brno, Brno-mesto, 656 53, Czechia
Mayo Clinic Cancer Center ( Site 0034)
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic Hospital ( Site 0013)
RECRUITING

Jacksonville, Florida, 32224, United States
McGill University Health Centre ( Site 0202)
RECRUITING

Montreal, Quebec, H4A 3J1, Canada
Medical University of South Carolina-Hollings Cancer Center ( Site 0016)
RECRUITING

Charleston, South Carolina, 29425, United States
Meir Medical Center. ( Site 4403)
RECRUITING

Kfar Saba, 4428164, Israel
Memorial Ankara Hastanesi ( Site 5116)
RECRUITING

Ankara, 06520, Turkey (Türkiye)
MemorialCare Health System - Long Beach Medical Center ( Site 9556)
RECRUITING

Long Beach, California, 90806, United States
Mercy Medical Center - Baltimore ( Site 0015)
RECRUITING

Baltimore, Maryland, 21202, United States
Metropolitan Hospital ( Site 4102)
RECRUITING

Athens, Attica, 185 47, Greece
Mie University Hospital ( Site 2312)
RECRUITING

Tsu, Mie-ken, 514-8507, Japan
Monash Health ( Site 1201)
RECRUITING

Clayton, Victoria, 3168, Australia
Municipal Enterprise "Bukovinian сlinical oncology сenter" ( Site 5208)
RECRUITING

Chernivtsi, Chernivetska Oblast, 58013, Ukraine
NL Health Services ( Site 0232)
RECRUITING

St. John's, Newfoundland and Labrador, A1B 3V6, Canada
Nagoya City University Hospital ( Site 2310)
RECRUITING

Nagoya, Aichi-ken, 467-8602, Japan
Naha Nishi Clinic ( Site 2320)
RECRUITING

Naha, Okinawa, 901-0154, Japan
Nakagami Hospital ( Site 2323)
RECRUITING

Okinawa, 904-2195, Japan
Nanjing Drum Tower Hospital ( Site 2217)
RECRUITING

Nanjing, Jiangsu, 210008, China
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Oddzial w Krakowie ( Site 4612)
RECRUITING

Krakow, Lesser Poland Voivodeship, 31-115, Poland
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Site 4609)
RECRUITING

Warsaw, Masovian Voivodeship, 02-781, Poland
Nashville General Hospital ( Site 0017)
RECRUITING

Nashville, Tennessee, 37208, United States
National Cancer Center ( Site 1800)
RECRUITING

Goyang-si, Kyonggi-do, 10408, South Korea
National Cancer Center Hospital ( Site 2305)
RECRUITING

Chūō, Tokyo, 104-0045, Japan
National Cancer Centre Singapore ( Site 1700)
RECRUITING

Singapore, Central Singapore, 168583, Singapore
National Cancer Institute ( Site 1501)
RECRUITING

Putrajaya, Putrajaya, 62250, Malaysia
National Hospital Organization Hokkaido Cancer Center ( Site 2300)
RECRUITING

Sapporo, Hokkaido, 003-0804, Japan
National Hospital Organization Osaka National Hospital ( Site 2315)
RECRUITING

Osaka, 540-0006, Japan
National Hospital Organization Shikoku Cancer Center ( Site 2319)
RECRUITING

Matsuyama, Ehime, 791-0280, Japan
National Taiwan University Cancer Center (NTUCC) ( Site 1901)
RECRUITING

Taipei, 106, Taiwan
National Taiwan University Hospital ( Site 1900)
RECRUITING

Taipei, 10048, Taiwan
Nemocnice AGEL Novy Jicin a.s.-Oddeleni radioterapie a onkologie ( Site 3401)
RECRUITING

Nový Jičín, Moravian-Silesian Region, 741 01, Czechia
New England Cancer Specialists ( Site 0051)
RECRUITING

Westbrook, Maine, 04092, United States
Ninewells Hospital and Medical School ( Site 5300)
RECRUITING

Dundee, Dundee City, DD2 1SG, United Kingdom
Nordlandssykehuset ( Site 3704)
RECRUITING

Bodø, Nordland, 8005, Norway
Northwest Cancer Specialists (Compass Oncology) ( Site 8010)
RECRUITING

Tigard, Oregon, 97223, United States
Northwest Medical Specialties, PLLC ( Site 0067)
RECRUITING

Tacoma, Washington, 98405, United States
Nottingham University Hospitals NHS Trust ( Site 5314)
RECRUITING

Nottingham, Nottinghamshire, NG5 1PB, United Kingdom
ONCOCENTRO APYS ( Site 6204)
RECRUITING

Viña del Mar, Valparaiso, 2520598, Chile
Ochsner Clinic Foundation ( Site 0021)
RECRUITING

New Orleans, Louisiana, 70121, United States
Onco Go, S.A ( Site 6402)
RECRUITING

Guatemala City, 01010, Guatemala
Oncologos del Occidente ( Site 6303)
RECRUITING

Pereira, Risaralda Department, 660001, Colombia
Oncology Consultants P.A. ( Site 0073)
RECRUITING

Houston, Texas, 77030, United States
Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 8005)
RECRUITING

Roanoke, Virginia, 24014, United States
Oncomedica ( Site 6405)
RECRUITING

Guatemala City, 01010, Guatemala
Oncosalud ( Site 6603)
RECRUITING

Lima, 15036, Peru
Optum Care Cancer Center ( Site 0050)
RECRUITING

Las Vegas, Nevada, 89102, United States
Országos Onkológiai Intézet-B-Belgyógyászati Onkológiai Osztály ( Site 4204)
RECRUITING

Budapest, 1122, Hungary
Ospedale San Raffaele di Milano ( Site 4515)
RECRUITING

Milan, 20132, Italy
Oulun yliopistollinen sairaala ( Site 3603)
RECRUITING

Oulu, North Ostrobothnia, 90220, Finland
PRONUTRIR ( Site 6120)
RECRUITING

Fortaleza, Ceará, 60810-180, Brazil
Pantai Hospital Kuala Lumpur ( Site 1500)
RECRUITING

Kuala Lumpur, 59100, Malaysia
Parc de Salut Mar - Hospital del Mar ( Site 5005)
RECRUITING

Barcelona, 08003, Spain
Prince of Wales Hospital ( Site 1301)
RECRUITING

Shatin, Hong Kong
Princess Margaret Cancer Centre ( Site 0208)
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Princess Royal University Hospital ( Site 5316)
RECRUITING

Orpington, Kent, BR6 8ND, United Kingdom
Promotora Médica Las Américas S.A. ( Site 6302)
RECRUITING

Medellín, Antioquia, 050025, Colombia
Providence Medical Foundation ( Site 0080)
RECRUITING

Fullerton, California, 92835, United States
Queen Mary Hospital ( Site 1300)
RECRUITING

Pokfulam, Hong Kong
Rambam Health Care Campus ( Site 4400)
RECRUITING

Haifa, 3109601, Israel
Renmin Hospital of Wuhan University ( Site 2236)
RECRUITING

Wuhan, Hubei, 430060, China
Renown Regional Medical Center ( Site 0041)
RECRUITING

Reno, Nevada, 89502, United States
Rocky Mountain Cancer Centers (RMCC) ( Site 8006)
RECRUITING

Denver, Colorado, 80220, United States
Roy and Patricia Disney Family Cancer Center ( Site 0055)
RECRUITING

Burbank, California, 91505, United States
Royal Victoria Regional Health Centre ( Site 0233)
RECRUITING

Barrie, Ontario, L4M 6M2, Canada
Rutgers Cancer Institute of New Jersey ( Site 0076)
RECRUITING

New Brunswick, New Jersey, 08901, United States
SC Radiotherapy Center Cluj SRL ( Site 4808)
RECRUITING

Cluj-Napoca, Cluj, 407280, Romania
SCRI Oncology Partners ( Site 7005)
RECRUITING

Nashville, Tennessee, 37203, United States
Saint Luke's Cancer Institute ( Site 0059)
RECRUITING

Kansas City, Missouri, 64111, United States
Salve Medica sp. z o.o. sp. k. ( Site 4618)
RECRUITING

Lodz, Łódź Voivodeship, 91-211, Poland
Samsun Medical Park Hastanesi ( Site 5121)
RECRUITING

Samsun, 55200, Turkey (Türkiye)
Samsung Medical Center ( Site 1807)
RECRUITING

Seoul, 06351, South Korea
Sanatorio Allende - Nueva Córdoba ( Site 6000)
RECRUITING

Córdoba, X5000BFB, Argentina
Sanatorio Finochietto ( Site 6007)
RECRUITING

Buenos Aires, C1187AAN, Argentina
Sanatorio Parque ( Site 6002)
RECRUITING

Rosario, Santa Fe Province, S2000DSV, Argentina
Sanatorio de la Cañada - Córdoba ( Site 6001)
RECRUITING

Córdoba, X5000BSQ, Argentina
Sandton Oncology Medical Group (Pty) Ltd ( Site 4900)
RECRUITING

Sandton, Gauteng, 2196, South Africa
Sarawak General Hospital ( Site 1504)
RECRUITING

Kuching, Sarawak, 93586, Malaysia
Sault Area Hospital ( Site 0226)
RECRUITING

Sault Ste. Marie, Ontario, P6B 0A8, Canada
Seoul National University Bundang Hospital ( Site 1801)
RECRUITING

Kyonggi-do, Kyonggi-do, 13620, South Korea
Seoul National University Hospital ( Site 1806)
RECRUITING

Seoul, 03080, South Korea
Severance Hospital Yonsei University Health System ( Site 1804)
RECRUITING

Seoul, 03722, South Korea
Shalimov Institute of Surgery and Transplantation ( Site 5210)
RECRUITING

Kyiv, 03126, Ukraine
Shandong Cancer Hospital ( Site 2205)
RECRUITING

Jinan, Shandong, 250117, China
Sheba Medical Center ( Site 4401)
RECRUITING

Ramat Gan, 5265601, Israel
Shizuoka Cancer Center ( Site 2309)
RECRUITING

Sunto-gun, Shizuoka, 411-8777, Japan
Showa Medical University Hospital ( Site 2306)
RECRUITING

Shinagawa, Tokyo, 142-8666, Japan
Skånes Universitetssjukhus Malmö ( Site 3802)
RECRUITING

Malmö, Skåne County, 20502, Sweden
Songklanagarind Hospital ( Site 2002)
RECRUITING

Hat Yai, Changwat Songkhla, 90110, Thailand
Specjalistyczny Szpital im. dra A. Sokolowskiego w Walbrzychu ( Site 4604)
RECRUITING

Wałbrzych, Lower Silesian Voivodeship, 58-309, Poland
Spitalul Clinic Filantropia ( Site 4801)
RECRUITING

Bucharest, 011132, Romania
St Bartholomew s Hospital ( Site 5302)
RECRUITING

London, London, City of, EC1A 7BE, United Kingdom
St Francis Cancer Center ( Site 0093)
RECRUITING

Greenville, South Carolina, 29607, United States
St. Vincenz-Krankenhaus Frauen- und Kinderklinik ( Site 4003)
RECRUITING

Paderborn, North Rhine-Westphalia, 33098, Germany
Stavanger Universitetssjukehus ( Site 3702)
RECRUITING

Stavanger, Rogaland, 4011, Norway
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zaklad Opieki Zdrowotnej ( Site 4619)
RECRUITING

Kielce, Świętokrzyskie Voivodeship, 25-734, Poland
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Onkoterapias Klinika ( Site 4202)
RECRUITING

Szeged, Csongrád megye, 6720, Hungary
Szpital Kliniczny Ministerstwa Spraw Wewnętrznych i Administracji z Warmińsko-Mazurskim Centrum Onko ( Site 4614)
RECRUITING

Olsztyn, Warmian-Masurian Voivodeship, 10-228, Poland
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie ( Site 4611)
RECRUITING

Koszalin, West Pomeranian Voivodeship, 75-581, Poland
Södra Älvsborgs Sjukhus Borås ( Site 3804)
RECRUITING

Borås, Västra Götaland County, 501 82, Sweden
THE MEDICAL CITY ( Site 1602)
RECRUITING

Pasig, National Capital Region, 1605, Philippines
Taichung Veterans General Hospital ( Site 1904)
RECRUITING

Taichung, 407, Taiwan
Tampereen ylipistollinen sairaala ( Site 3601)
RECRUITING

Tampere, Pirkanmaa, 33520, Finland
Tennessee Cancer Specialists ( Site 7001)
RECRUITING

Knoxville, Tennessee, 37909, United States
Texas Oncology - DFW ( Site 8009)
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology - Northeast Texas ( Site 8002)
RECRUITING

Flower Mound, Texas, 75028, United States
Texas Oncology - San Antonio ( Site 8004)
RECRUITING

San Antonio, Texas, 78240, United States
Texas Tech University Health Sciences Center ( Site 0087)
RECRUITING

Lubbock, Texas, 79430, United States
The Catholic University of Korea. Seoul St. Mary s Hospital ( Site 1802)
RECRUITING

Seoul, 06591, South Korea
The First Affiliated Hospital of Xi'an Jiaotong University ( Site 2203)
RECRUITING

Xi'an, Shaanxi, 710000, China
The First Affiliated hospital of Xiamen University-Breast Surgery ( Site 2224)
RECRUITING

Xiamen, Fujian, 361009, China
The First Hospital Of Jilin University ( Site 2207)
RECRUITING

Changchun, Jilin, 130021, China
The Ottawa Hospital - General Campus-The Ottawa Hospital Cancer Centre ( Site 0209)
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
The Second Affiliated Hospital Zhejiang University School of Medicine ( Site 2212)
RECRUITING

Hangzhou, Zhejiang, 310017, China
The Second People's Hospital of Neijiang ( Site 2242)
RECRUITING

Neijiang, Sichuan, 641099, China
The Third Hospital Of Nanchang ( Site 2218)
RECRUITING

Nanchang, Jiangxi, 330025, China
The University of Osaka Hospital ( Site 2314)
RECRUITING

Suita, Osaka, 565-0871, Japan
Toranomon Hospital ( Site 2307)
RECRUITING

Minato, Tokyo, 105-8470, Japan
Tuen Mun Hospital ( Site 1303)
RECRUITING

Tuenmen, Hong Kong
UZ Gent ( Site 3202)
RECRUITING

Ghent, Oost-Vlaanderen, 9000, Belgium
Unidade Local de Saude Lisboa Ocidental - Hospital de São Francisco Xavier ( Site 4702)
RECRUITING

Lisbon, Lisbon District, 1449-005, Portugal
Unidade Local de Saúde de São João ( Site 4703)
RECRUITING

Porto, 4200-319, Portugal
Universitaetsklinik Erlangen ( Site 4001)
RECRUITING

Erlangen, Bavaria, 91054, Germany
University College London Hospital ( Site 5301)
RECRUITING

London, Camden, NW1 2PG, United Kingdom
University Malaya Medical Centre. ( Site 1503)
RECRUITING

Lembah Pantai, Kuala Lumpur, 59100, Malaysia
University of Arizona Cancer Center ( Site 0035)
RECRUITING

Tucson, Arizona, 85719, United States
University of Wisconsin-Madison ( Site 0024)
RECRUITING

Madison, Wisconsin, 53792, United States
Vanderbilt-Ingram Cancer Center ( Site 0038)
RECRUITING

Nashville, Tennessee, 37232, United States
Virginia Oncology Associates (VOA) ( Site 8008)
RECRUITING

Norfolk, Virginia, 23502, United States
Washington University Siteman Cancer Center ( Site 0031)
RECRUITING

St Louis, Missouri, 63110, United States
Westmead Hospital ( Site 1200)
RECRUITING

Westmead, New South Wales, 2145, Australia
Wits Clinical Research ( Site 4903)
RECRUITING

Johannesburg, Gauteng, 2193, South Africa
Wojewódzki Szpital Specjalistyczny im. J. Korczaka w Słupsku ( Site 4600)
RECRUITING

Słupsk, Pomeranian Voivodeship, 76-200, Poland
Wuhan Union Hospital ( Site 2239)
RECRUITING

Wuhan, Hubei, 430000, China
Xiangya Hospital of Central South University ( Site 2225)
RECRUITING

Changsha, Hunan, 410008, China
Xingtai People's Hospital ( Site 2260)
RECRUITING

Xingtai, Hebei, 054001, China
Xinjiang Medical University Cancer Hospital - Urumqi ( Site 2230)
RECRUITING

Ürümqi, Xinjiang, 830000, China
Yitzhak Shamir Medical Center. ( Site 4404)
RECRUITING

Ẕerifin, 70300, Israel
Yunnan Province Cancer Hospital ( Site 2226)
RECRUITING

Kunming, Yunnan, 650118, China
Zala Vármegyei Szent Rafael Kórház-Onkológiai osztály ( Site 4206)
RECRUITING

Zalaegerszeg, Zala County, 8900, Hungary
Zhejiang Cancer Hospital ( Site 2211)
ACTIVE_NOT_RECRUITING

Hangzhou, Zhejiang, 310022, China
Zhejiang Provincial People's Hospital ( Site 2215)
RECRUITING

Hangzhou, Zhejiang, 311599, China
centre hospitalier lyon sud ( Site 3901)
RECRUITING

Pierre-Bénite, Rhone, 69310, France

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